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RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma.
Jermakowicz AM, Kurimchak AM, Johnson KJ, Bourgain-Guglielmetti F, Kaeppeli S, Affer M, Pradhyumnan H, Suter RK, Walters W, Cepero M, Duncan JS, Ayad NG. Jermakowicz AM, et al. Among authors: ayad ng. Sci Rep. 2024 Apr 23;14(1):9284. doi: 10.1038/s41598-024-60031-8. Sci Rep. 2024. PMID: 38654040 Free PMC article.
Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models.
Rodriguez-Blanco J, Salvador AD, Suter RK, Swiderska-Syn M, Palomo-Caturla I, Kliebe V, Shahani P, Peterson K, Turos-Cabal M, Vieira ME, Wynn DT, Howell AJ, Yang F, Ban Y, McCrea HJ, Zindy F, Danis E, Vibhakar R, Jermakowicz A, Martin V, Coss CC, Harris BT, de Cubas A, Chen XS, Barnoud T, Roussel MF, Ayad NG, Robbins DJ. Rodriguez-Blanco J, et al. Among authors: ayad ng. J Clin Invest. 2024 Jun 17;134(15):e171136. doi: 10.1172/JCI171136. J Clin Invest. 2024. PMID: 38885332 Free PMC article.
Glutaminase 2 as a therapeutic target in glioblastoma.
Veeramachaneni RK, Suter RK, Rowland E, Jermakowicz A, Ayad NG. Veeramachaneni RK, et al. Among authors: ayad ng. Biochim Biophys Acta Rev Cancer. 2024 Nov;1879(6):189182. doi: 10.1016/j.bbcan.2024.189182. Epub 2024 Sep 16. Biochim Biophys Acta Rev Cancer. 2024. PMID: 39293549 Free article. Review.
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, Chiang CM, Xu M, Chen Y, Yang FC. Yang H, et al. Among authors: ayad ng. EMBO Rep. 2023 Oct 9;24(10):e57032. doi: 10.15252/embr.202357032. Epub 2023 Aug 31. EMBO Rep. 2023. PMID: 37650863 Free PMC article.
Kinome-Wide Virtual Screening by Multi-Task Deep Learning.
Hu J, Allen BK, Stathias V, Ayad NG, Schürer SC. Hu J, et al. Among authors: ayad ng. Int J Mol Sci. 2024 Feb 22;25(5):2538. doi: 10.3390/ijms25052538. Int J Mol Sci. 2024. PMID: 38473785 Free PMC article.
56 results