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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs.
Guo H, Vuille JA, Wittner BS, Lachtara EM, Hou Y, Lin M, Zhao T, Raman AT, Russell HC, Reeves BA, Pleskow HM, Wu CL, Gnirke A, Meissner A, Efstathiou JA, Lee RJ, Toner M, Aryee MJ, Lawrence MS, Miyamoto DT, Maheswaran S, Haber DA. Guo H, et al. Among authors: lachtara em. Cell. 2023 Jun 22;186(13):2765-2782.e28. doi: 10.1016/j.cell.2023.05.028. Epub 2023 Jun 15. Cell. 2023. PMID: 37327786 Free PMC article.
The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Yang H, Lachtara EM, Ran X, Hopkins J, Patel PS, Zhu X, Xiao Y, Phoon L, Gao B, Zou L, Lawrence MS, Lan L. Yang H, et al. Among authors: lachtara em. Nat Commun. 2023 Sep 30;14(1):6114. doi: 10.1038/s41467-023-41790-w. Nat Commun. 2023. PMID: 37777505 Free PMC article.