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Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.
Courlet P, Abler D, Guidi M, Girard P, Amato F, Vietti Violi N, Dietz M, Guignard N, Wicky A, Latifyan S, De Micheli R, Jreige M, Dromain C, Csajka C, Prior JO, Venkatakrishnan K, Michielin O, Cuendet MA, Terranova N. Courlet P, et al. Among authors: venkatakrishnan k. CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1170-1181. doi: 10.1002/psp4.12983. Epub 2023 Jun 16. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37328961 Free PMC article.
A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer.
Liu H, Milenković-Grišić AM, Krishnan SM, Jönsson S, Friberg LE, Girard P, Venkatakrishnan K, Vugmeyster Y, Khandelwal A, Karlsson MO. Liu H, et al. Among authors: venkatakrishnan k. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1738-1750. doi: 10.1002/psp4.12976. Epub 2023 May 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37165943 Free PMC article.
Future Opportunities in Drug Development: American Society for Clinical Pharmacology and Therapeutics Pharmacometrics and Pharmacokinetics Community Vision.
Burton J, Abuasal B, Bachhav S, Connarn J, Cosman J, Gupta N, Jing J, Kim S, Long T, Terranova N, Venkatakrishnan K, Wang J, Liu Q. Burton J, et al. Among authors: venkatakrishnan k. Clin Pharmacol Ther. 2023 Sep;114(3):507-510. doi: 10.1002/cpt.2955. Epub 2023 Jun 11. Clin Pharmacol Ther. 2023. PMID: 37303106 No abstract available.
Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non-small cell lung cancer based on bintrafusp alfa trials.
Milenković-Grišić AM, Terranova N, Mould DR, Vugmeyster Y, Mrowiec T, Machl A, Girard P, Venkatakrishnan K, Khandelwal A. Milenković-Grišić AM, et al. Among authors: venkatakrishnan k. CPT Pharmacometrics Syst Pharmacol. 2024 Jan;13(1):143-153. doi: 10.1002/psp4.13068. Epub 2023 Dec 13. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38087967 Free PMC article.
Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase-CYP substrates.
Izat N, Bolleddula J, Carione P, Huertas Valentin L, Jones RS, Kulkarni P, Moss D, Peterkin VC, Tian DD, Treyer A, Venkatakrishnan K, Zientek MA, Barber J, Houston JB, Galetin A, Scotcher D. Izat N, et al. Among authors: venkatakrishnan k. CPT Pharmacometrics Syst Pharmacol. 2025 Jan;14(1):164-178. doi: 10.1002/psp4.13255. Epub 2024 Oct 23. CPT Pharmacometrics Syst Pharmacol. 2025. PMID: 39444174 Free PMC article.
Challenges and Opportunities for In Vitro-In Vivo Extrapolation of Aldehyde Oxidase-Mediated Clearance: Toward a Roadmap for Quantitative Translation.
Izat N, Bolleddula J, Abbasi A, Cheruzel L, Jones RS, Moss D, Ortega-Muro F, Parmentier Y, Peterkin VC, Tian DD, Venkatakrishnan K, Zientek MA, Barber J, Houston JB, Galetin A, Scotcher D. Izat N, et al. Among authors: venkatakrishnan k. Drug Metab Dispos. 2023 Dec;51(12):1591-1606. doi: 10.1124/dmd.123.001436. Epub 2023 Sep 26. Drug Metab Dispos. 2023. PMID: 37751998
311 results