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CAR T-cell design dependent remodeling of the brain tumor immune microenvironment identify macrophages as key players that inhibit or promote anti-tumor activity.
Haydar D, Ibañez-Vega J, Crawford JC, Chou CH, Guy C, Meehl M, Yi Z, Langfitt D, Vogel P, DeRenzo C, Gottschalk S, Roussel MF, Thomas PG, Krenciute G. Haydar D, et al. Among authors: chou ch. Res Sq [Preprint]. 2023 Jun 6:rs.3.rs-2972427. doi: 10.21203/rs.3.rs-2972427/v1. Res Sq. 2023. Update in: Cancer Res Commun. 2023 Dec 1;3(12):2430-2446. doi: 10.1158/2767-9764.CRC-23-0424 PMID: 37333156 Free PMC article. Updated. Preprint.
SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8 T cells.
Minervina AA, Pogorelyy MV, Kirk AM, Crawford JC, Allen EK, Chou CH, Mettelman RC, Allison KJ, Lin CY, Brice DC, Zhu X, Vegesana K, Wu G, Trivedi S, Kottapalli P, Darnell D, McNeely S, Olsen SR, Schultz-Cherry S, Estepp JH; SJTRC Study Team; McGargill MA, Wolf J, Thomas PG. Minervina AA, et al. Among authors: chou ch. medRxiv [Preprint]. 2022 Jan 26:2021.07.12.21260227. doi: 10.1101/2021.07.12.21260227. medRxiv. 2022. Update in: Nat Immunol. 2022 May;23(5):781-790. doi: 10.1038/s41590-022-01184-4 PMID: 34341799 Free PMC article. Updated. Preprint.
DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma.
Kirk AM, Crawford JC, Chou CH, Guy C, Pandey K, Kozlik T, Shah RK, Chung S, Nguyen P, Zhang X, Wang J, Bell M, Mettelman RC, Allen EK, Pogorelyy MV, Kim H, Minervina AA, Awad W, Bajracharya R, White T, Long D Jr, Gordon B, Morrison M, Glazer ES, Murphy AJ, Jiang Y, Fitzpatrick EA, Yarchoan M, Sethupathy P, Croft NP, Purcell AW, Federico SM, Stewart E, Gottschalk S, Zamora AE, DeRenzo C, Strome SE, Thomas PG. Kirk AM, et al. Among authors: chou ch. Cell Rep Med. 2024 Mar 19;5(3):101469. doi: 10.1016/j.xcrm.2024.101469. Cell Rep Med. 2024. PMID: 38508137 Free PMC article.
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening.
Lin TE, Chou CH, Wu YW, Sung TY, Hsu JY, Yen SC, Hsieh JH, Chang YW, Pan SL, Huang WJ, Hsu KC, Yang CR. Lin TE, et al. Among authors: chou ch. J Chem Inf Model. 2025 Jan 13;65(1):378-389. doi: 10.1021/acs.jcim.4c02011. Epub 2024 Dec 31. J Chem Inf Model. 2025. PMID: 39740163 Free PMC article.
954 results