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56 Fe ion exposure increases the incidence of lung and brain tumors at a similar rate in male and female mice.
Finkelstein SR, Patel R, Deland K, Mercer J, Starr B, Zhu D, Min H, Reinsvold M, Campos LDS, Williams N, Luo L, Ma Y, Neff J, Hoenerhoff M, Moding EJ, Kirsch DG. Finkelstein SR, et al. Among authors: kirsch dg. bioRxiv [Preprint]. 2023 Jun 8:2023.06.06.543754. doi: 10.1101/2023.06.06.543754. bioRxiv. 2023. Update in: Radiat Res. 2024 Nov 1;202(5):734-744. doi: 10.1667/RADE-24-00004.1 PMID: 37333373 Free PMC article. Updated. Preprint.
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis I, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Among authors: kirsch dg. bioRxiv [Preprint]. 2023 Apr 28:2023.04.27.538576. doi: 10.1101/2023.04.27.538576. bioRxiv. 2023. Update in: Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8 PMID: 37162959 Free PMC article. Updated. Preprint.
Mis-splicing Drives Loss of Function of p53E224D Point Mutation.
Lock IC, Leisenring NH, Floyd W, Xu ES, Luo L, Ma Y, Mansell EC, Cardona DM, Lee CL, Kirsch DG. Lock IC, et al. Among authors: kirsch dg. bioRxiv [Preprint]. 2023 Aug 3:2023.08.01.551439. doi: 10.1101/2023.08.01.551439. bioRxiv. 2023. PMID: 37577531 Free PMC article. Preprint.
Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models.
Hendrickson PG, Oristian KM, Browne MR, Lou L, Ma Y, Cardona DM, Linardic CM, Kirsch DG. Hendrickson PG, et al. Among authors: kirsch dg. bioRxiv [Preprint]. 2023 Sep 28:2023.09.26.559519. doi: 10.1101/2023.09.26.559519. bioRxiv. 2023. Update in: Oncogene. 2024 Apr;43(16):1223-1230. doi: 10.1038/s41388-024-02984-8 PMID: 37808628 Free PMC article. Updated. Preprint.
Ataxia-telangiectasia mutated ( Atm ) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy.
Mangoli A, Wu S, Liu HQ, Aksu M, Jain V, Foreman BE, Regal JA, Weidenhammer LB, Stewart CE, Guerra Garcia ME, Hocke E, Abramson K, Williams NT, Luo L, Deland K, Attardi L, Abe K, Hashizume R, Ashley DM, Becher OJ, Kirsch DG, Gregory SG, Reitman ZJ. Mangoli A, et al. Among authors: kirsch dg. bioRxiv [Preprint]. 2023 Oct 20:2023.10.18.562892. doi: 10.1101/2023.10.18.562892. bioRxiv. 2023. PMID: 37904990 Free PMC article. Preprint.
270 results