Hardy JM - Search Results

1

Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.

Roy MJ, Surudoi MG, Kropp A, Hou J, Dai W, Hardy JM, Liang LY, Cotton TR, Lechtenberg BC, Dite TA, Ma X, Daly RJ, Patel O, Lucet IS. Roy MJ, et al. Among authors: hardy jm. Nat Commun. 2023 Jun 19;14(1):3542. doi: 10.1038/s41467-023-38869-9. Nat Commun. 2023. PMID: 37336884 Free PMC article.

2

Structural insights into the assembly and regulation of distinct viral capsid complexes.

Sarker S, Terrón MC, Khandokar Y, Aragão D, Hardy JM, Radjainia M, Jiménez-Zaragoza M, de Pablo PJ, Coulibaly F, Luque D, Raidal SR, Forwood JK. Sarker S, et al. Among authors: hardy jm. Nat Commun. 2016 Oct 4;7:13014. doi: 10.1038/ncomms13014. Nat Commun. 2016. PMID: 27698405 Free PMC article.

3

The architecture and stabilisation of flagellotropic tailed bacteriophages.

Hardy JM, Dunstan RA, Grinter R, Belousoff MJ, Wang J, Pickard D, Venugopal H, Dougan G, Lithgow T, Coulibaly F. Hardy JM, et al. Nat Commun. 2020 Jul 27;11(1):3748. doi: 10.1038/s41467-020-17505-w. Nat Commun. 2020. PMID: 32719311 Free PMC article.

4

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses.

Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D. Hardy JM, et al. Nat Commun. 2021 Jun 1;12(1):3266. doi: 10.1038/s41467-021-22773-1. Nat Commun. 2021. PMID: 34075032 Free PMC article.

5

Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1.

Patel O, Roy MJ, Kropp A, Hardy JM, Dai W, Lucet IS. Patel O, et al. Among authors: hardy jm. Commun Biol. 2021 Sep 20;4(1):1105. doi: 10.1038/s42003-021-02631-y. Commun Biol. 2021. PMID: 34545159 Free PMC article.

6

Production and purification of the PEAK pseudokinases for structural and functional studies.

Patel O, Surudoi M, Dai W, Hardy JM, Roy MJ, Lucet IS. Patel O, et al. Among authors: hardy jm. Methods Enzymol. 2022;667:1-35. doi: 10.1016/bs.mie.2022.03.022. Epub 2022 Apr 25. Methods Enzymol. 2022. PMID: 35525538

7

Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis.

Carli ALE, Hardy JM, Hoblos H, Ernst M, Lucet IS, Buchert M. Carli ALE, et al. Among authors: hardy jm. Biomedicines. 2023 Mar 22;11(3):990. doi: 10.3390/biomedicines11030990. Biomedicines. 2023. PMID: 36979969 Free PMC article. Review.

8

Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin.

Sarson-Lawrence KTG, Hardy JM, Iaria J, Stockwell D, Behrens K, Saiyed T, Tan C, Jebeli L, Scott NE, Dite TA, Nicola NA, Leis AP, Babon JJ, Kershaw NJ. Sarson-Lawrence KTG, et al. Among authors: hardy jm. Nat Commun. 2024 Feb 7;15(1):1135. doi: 10.1038/s41467-024-45356-2. Nat Commun. 2024. PMID: 38326297 Free PMC article.

9

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses.

Amarilla AA, Sng JDJ, Parry R, Deerain JM, Potter JR, Setoh YX, Rawle DJ, Le TT, Modhiran N, Wang X, Peng NYG, Torres FJ, Pyke A, Harrison JJ, Freney ME, Liang B, McMillan CLD, Cheung STM, Guevara DJDC, Hardy JM, Bettington M, Muller DA, Coulibaly F, Moore F, Hall RA, Young PR, Mackenzie JM, Hobson-Peters J, Suhrbier A, Watterson D, Khromykh AA. Amarilla AA, et al. Among authors: hardy jm. Nat Commun. 2021 Jun 8;12(1):3431. doi: 10.1038/s41467-021-23779-5. Nat Commun. 2021. PMID: 34103499 Free PMC article.

10

The nucleocapsid architecture and structural atlas of the prototype baculovirus define the hallmarks of a new viral realm.

Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F. Johnstone BA, et al. Among authors: hardy jm. Sci Adv. 2024 Dec 20;10(51):eado2631. doi: 10.1126/sciadv.ado2631. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693434 Free PMC article.

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