Wessels AM - Search Results

1

'Time Saved' As a Demonstration of Clinical Meaningfulness and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings.

Dickson SP, Wessels AM, Dowsett SA, Mallinckrodt C, Sparks JD, Chatterjee S, Hendrix S. Dickson SP, et al. Among authors: wessels am. J Prev Alzheimers Dis. 2023;10(3):595-599. doi: 10.14283/jpad.2023.50. J Prev Alzheimers Dis. 2023. PMID: 37357301

2

Meaningful Clinical Changes in Alzheimer Disease Measured With the iADRS and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings.

Wessels AM, Dennehy EB, Dowsett SA, Dickson SP, Hendrix SB. Wessels AM, et al. Neurol Clin Pract. 2023 Apr;13(2):e200127. doi: 10.1212/CPJ.0000000000200127. Epub 2023 Feb 16. Neurol Clin Pract. 2023. PMID: 36891463 Free PMC article. Review.

3

Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.

Sims JR, Zimmer JA, Evans CD, Lu M, Ardayfio P, Sparks J, Wessels AM, Shcherbinin S, Wang H, Monkul Nery ES, Collins EC, Solomon P, Salloway S, Apostolova LG, Hansson O, Ritchie C, Brooks DA, Mintun M, Skovronsky DM; TRAILBLAZER-ALZ 2 Investigators. Sims JR, et al. Among authors: wessels am. JAMA. 2023 Aug 8;330(6):512-527. doi: 10.1001/jama.2023.13239. JAMA. 2023. PMID: 37459141 Free PMC article.

4

How donanemab data address the coverage with evidence development questions.

Klein EG, Schroeder K, Wessels AM, Phipps A, Japha M, Schilling T, Zimmer JA. Klein EG, et al. Among authors: wessels am. Alzheimers Dement. 2024 Apr;20(4):3127-3140. doi: 10.1002/alz.13700. Epub 2024 Feb 7. Alzheimers Dement. 2024. PMID: 38323738 Free PMC article. Review.

5

Clinical Meaningfulness in Alzheimer's Disease Clinical Trials. A Report from the EU-US CTAD Task Force.

Angioni D, Cummings J, Lansdall CJ, Middleton L, Sampaio C, Gauthier S, Cohen S, Petersen RC, Rentz DM, Wessels AM, Hendrix SB, Jessen F, Carrillo MC, Doody RS, Irizarry M, Andrews JS, Vellas B, Aisen P. Angioni D, et al. Among authors: wessels am. J Prev Alzheimers Dis. 2024;11(5):1219-1227. doi: 10.14283/jpad.2024.112. J Prev Alzheimers Dis. 2024. PMID: 39350367 Free PMC article.

6

Disease progression model using the integrated Alzheimer's Disease Rating Scale.

Gueorguieva I, Chua L, Willis BA, Sims JR, Wessels AM. Gueorguieva I, et al. Among authors: wessels am. Alzheimers Dement. 2023 Jun;19(6):2253-2264. doi: 10.1002/alz.12876. Epub 2022 Nov 30. Alzheimers Dement. 2023. PMID: 36450003

7

Digital spacer data driven COPD inhaler adherence education: The OUTERSPACE proof-of-concept study.

Dierick BJH, Been-Buck S, Klemmeier T, Hagedoorn P, van de Hei SJ, Kerstjens HAM, Kocks JWH, Zijp TR, Wessels AMA, Touw DJ, van Boven JFM. Dierick BJH, et al. Among authors: wessels ama. Respir Med. 2022 Sep;201:106940. doi: 10.1016/j.rmed.2022.106940. Epub 2022 Jul 31. Respir Med. 2022. PMID: 35933835 Free article.

8

Demonstration of Clinical Meaningfulness of the Integrated Alzheimer's Disease Rating Scale (iADRS): Association Between Change in iADRS Scores and Patient and Caregiver Health Outcomes.

Wessels AM, Belger M, Johnston JA, Yu Y, Rentz DM, Dowsett SA, Chandler J. Wessels AM, et al. J Alzheimers Dis. 2022;88(2):577-588. doi: 10.3233/JAD-220303. J Alzheimers Dis. 2022. PMID: 35694928 Free PMC article.

9

Integrated Alzheimer's Disease Rating Scale: Clinically meaningful change estimates.

Wessels AM, Rentz DM, Case M, Lauzon S, Sims JR. Wessels AM, et al. Alzheimers Dement (N Y). 2022 Jun 6;8(1):e12312. doi: 10.1002/trc2.12312. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35676941 Free PMC article.

10

Extending the viability of human precision-cut intestinal slice model for drug metabolism studies.

Biel C, Martinec O, Sibering B, van Summeren K, Wessels AMA, Touw DJ, de Jong KP, de Meijer VE, Faber KN, Klooster JPT, de Graaf IAM, Olinga P. Biel C, et al. Among authors: wessels ama. Arch Toxicol. 2022 Jun;96(6):1815-1827. doi: 10.1007/s00204-022-03295-1. Epub 2022 Apr 15. Arch Toxicol. 2022. PMID: 35428896 Free PMC article.

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