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Lacteal junction zippering protects against diet-induced obesity.
Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A. Zhang F, et al. Among authors: dubrac a. Science. 2018 Aug 10;361(6402):599-603. doi: 10.1126/science.aap9331. Science. 2018. PMID: 30093598 Free PMC article.
Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.
Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, Li J, Genet N, Henrique Geraldo L, Benedetti L, Künzel S, Pibouin-Fragner L, Thomas JL, Eichmann A. Genet G, et al. Among authors: dubrac a. Nat Commun. 2019 May 28;10(1):2350. doi: 10.1038/s41467-019-10359-x. Nat Commun. 2019. PMID: 31138815 Free PMC article.
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.
Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, Chaney SY, Pilon F, Dogan T, Cagnone G, Patel P, Buscarlet M, Dasgupta S, Girouard G, Rao SR, Wilson AM, O'Brien R, Juneau R, Guber V, Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P. Crespo-Garcia S, et al. Among authors: dubrac a. Cell Metab. 2021 Apr 6;33(4):818-832.e7. doi: 10.1016/j.cmet.2021.01.011. Epub 2021 Feb 5. Cell Metab. 2021. PMID: 33548171 Free article.
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter IM, Gordon E, Dubrac A, Ragab A, Narloch J, Vizán P, Geudens I, Collins RT, Franco CA, Abrahams CL, Thurston G, Fruttiger M, Rosewell I, Eichmann A, Gerhardt H. Aspalter IM, et al. Among authors: dubrac a. Nat Commun. 2015 Jun 17;6:7264. doi: 10.1038/ncomms8264. Nat Commun. 2015. PMID: 26081042 Free PMC article.
RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.
Tetik-Elsherbiny N, Elsherbiny A, Setya A, Gahn J, Tang Y, Gupta P, Dou Y, Serke H, Wieland T, Dubrac A, Heineke J, Potente M, Cordero J, Ola R, Dobreva G. Tetik-Elsherbiny N, et al. Among authors: dubrac a. Nat Cardiovasc Res. 2024 Oct;3(10):1199-1216. doi: 10.1038/s44161-024-00546-5. Epub 2024 Sep 25. Nat Cardiovasc Res. 2024. PMID: 39322771 Free PMC article.
39 results