Mangrum MM - Search Results

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Caspofungin-induced β(1,3)-glucan exposure in Candida albicans is driven by increased chitin levels.

Wagner AS, Lumsdaine SW, Mangrum MM, Reynolds TB. Wagner AS, et al. Among authors: mangrum mm. mBio. 2023 Aug 31;14(4):e0007423. doi: 10.1128/mbio.00074-23. Epub 2023 Jun 28. mBio. 2023. PMID: 37377417 Free PMC article.

Activation of Cph1 causes ß(1,3)-glucan unmasking in Candida albicans and attenuates virulence in mice in a neutrophil-dependent manner.

Wagner AS, Hancock TJ, Lumsdaine SW, Kauffman SJ, Mangrum MM, Phillips EK, Sparer TE, Reynolds TB. Wagner AS, et al. Among authors: mangrum mm. PLoS Pathog. 2021 Aug 25;17(8):e1009839. doi: 10.1371/journal.ppat.1009839. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34432857 Free PMC article.

Cek1 regulates ß(1,3)-glucan exposure through calcineurin effectors in Candida albicans.

Wagner AS, Lumsdaine SW, Mangrum MM, King AE, Hancock TJ, Sparer TE, Reynolds TB. Wagner AS, et al. Among authors: mangrum mm. PLoS Genet. 2022 Sep 19;18(9):e1010405. doi: 10.1371/journal.pgen.1010405. eCollection 2022 Sep. PLoS Genet. 2022. PMID: 36121853 Free PMC article.

The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase.

Zhou Y, Phelps GA, Mangrum MM, McLeish J, Phillips EK, Lou J, Ancajas CF, Rybak JM, Oelkers PM, Lee RE, Best MD, Reynolds TB. Zhou Y, et al. Among authors: mangrum mm. mBio. 2024 May 8;15(5):e0063324. doi: 10.1128/mbio.00633-24. Epub 2024 Apr 9. mBio. 2024. PMID: 38587428 Free PMC article.

Disruption to de novo uridine biosynthesis alters β-1,3-glucan masking in Candida albicans.

Mangrum MM, Vogel AK, Wagner AS, King AE, Miao J, Zhou Y, Phillips EK, Peters BM, Reynolds TB. Mangrum MM, et al. mSphere. 2024 Sep 25;9(9):e0028724. doi: 10.1128/msphere.00287-24. Epub 2024 Aug 8. mSphere. 2024. PMID: 39115319 Free PMC article.

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