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An engineered xCas12i with high activity, high specificity, and broad PAM range.
Zhang H, Kong X, Xue M, Hu J, Wang Z, Wei Y, Wang H, Zhou J, Zhang W, Xu M, Shen X, Yin F, Ai Z, Huang G, Xia J, Song X, Li H, Yuan Y, Li J, Zhong N, Zhang M, Zhou Y, Yang H. Zhang H, et al. Among authors: zhang m, zhang w. Protein Cell. 2023 Jun 28;14(7):538-543. doi: 10.1093/procel/pwac052. Protein Cell. 2023. PMID: 37378659 Free PMC article. No abstract available.
Development of miniature base editors using engineered IscB nickase.
Han D, Xiao Q, Wang Y, Zhang H, Dong X, Li G, Kong X, Wang S, Song J, Zhang W, Zhou J, Bi L, Yuan Y, Shi L, Zhong N, Yang H, Zhou Y. Han D, et al. Among authors: zhang w, zhang h. Nat Methods. 2023 Jul;20(7):1029-1036. doi: 10.1038/s41592-023-01898-9. Epub 2023 May 25. Nat Methods. 2023. PMID: 37231266
Engineering a transposon-associated TnpB-ωRNA system for efficient gene editing and phenotypic correction of a tyrosinaemia mouse model.
Li Z, Guo R, Sun X, Li G, Shao Z, Huo X, Yang R, Liu X, Cao X, Zhang H, Zhang W, Zhang X, Ma S, Zhang M, Liu Y, Yao Y, Shi J, Yang H, Hu C, Zhou Y, Xu C. Li Z, et al. Among authors: zhang m, zhang w, zhang h, zhang x. Nat Commun. 2024 Jan 27;15(1):831. doi: 10.1038/s41467-024-45197-z. Nat Commun. 2024. PMID: 38280857 Free PMC article.
Drug Development.
Bhuiyan P, Zhang W, Chae R, Kim K, St Louis L, Wang Y, Liang G, Wei H. Bhuiyan P, et al. Among authors: zhang w. Alzheimers Dement. 2024 Dec;20 Suppl 6:e089764. doi: 10.1002/alz.089764. Alzheimers Dement. 2024. PMID: 39782661
Drug Development.
Smith NS, Burr HJ, Zhang W, Wang C. Smith NS, et al. Among authors: zhang w. Alzheimers Dement. 2024 Dec;20 Suppl 6:e087705. doi: 10.1002/alz.087705. Alzheimers Dement. 2024. PMID: 39782618
Drug Development.
Bhuiyan P, Zhang W, Chae R, Kim K, St Louis L, Wang Y, Liang G, Liu J, Wei H. Bhuiyan P, et al. Among authors: zhang w. Alzheimers Dement. 2024 Dec;20 Suppl 6:e089654. doi: 10.1002/alz.089654. Alzheimers Dement. 2024. PMID: 39782574
Drug Development.
Burr HJ, Smith NS, Zhang W, Wang C. Burr HJ, et al. Among authors: zhang w. Alzheimers Dement. 2024 Dec;20 Suppl 6:e093558. doi: 10.1002/alz.093558. Alzheimers Dement. 2024. PMID: 39782467
Dementia Care Research and Psychosocial Factors.
Powell D, Zhang W, Coresh J, Kucharska-Newton AM, Kent E, Saylor MA, Ballew S, Ornstein K, Deal JA, Reed NS. Powell D, et al. Among authors: zhang w. Alzheimers Dement. 2024 Dec;20 Suppl 4:e084436. doi: 10.1002/alz.084436. Alzheimers Dement. 2024. PMID: 39782316
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