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An engineered xCas12i with high activity, high specificity, and broad PAM range.
Zhang H, Kong X, Xue M, Hu J, Wang Z, Wei Y, Wang H, Zhou J, Zhang W, Xu M, Shen X, Yin F, Ai Z, Huang G, Xia J, Song X, Li H, Yuan Y, Li J, Zhong N, Zhang M, Zhou Y, Yang H. Zhang H, et al. Among authors: zhou y, zhou j. Protein Cell. 2023 Jun 28;14(7):538-543. doi: 10.1093/procel/pwac052. Protein Cell. 2023. PMID: 37378659 Free PMC article. No abstract available.
Development of miniature base editors using engineered IscB nickase.
Han D, Xiao Q, Wang Y, Zhang H, Dong X, Li G, Kong X, Wang S, Song J, Zhang W, Zhou J, Bi L, Yuan Y, Shi L, Zhong N, Yang H, Zhou Y. Han D, et al. Among authors: zhou y, zhou j. Nat Methods. 2023 Jul;20(7):1029-1036. doi: 10.1038/s41592-023-01898-9. Epub 2023 May 25. Nat Methods. 2023. PMID: 37231266
Engineered IscB-ωRNA system with expanded target range for base editing.
Xiao Q, Li G, Han D, Wang H, Yao M, Ma T, Zhou J, Zhang Y, Zhang X, He B, Yuan Y, Shi L, Li T, Yang H, Huang J, Zhang H. Xiao Q, et al. Among authors: zhou j. Nat Chem Biol. 2025 Jan;21(1):100-108. doi: 10.1038/s41589-024-01706-1. Epub 2024 Aug 15. Nat Chem Biol. 2025. PMID: 39147927 Free PMC article.
Technology and Dementia Preconference.
Qin S, Ng EKK, Soon C, Chua X, Zhou JH, Koh WP, Chee MW. Qin S, et al. Among authors: zhou jh. Alzheimers Dement. 2024 Dec;20 Suppl 10:e094183. doi: 10.1002/alz.094183. Alzheimers Dement. 2024. PMID: 39781779
Technology and Dementia Preconference.
Hoang B, Pang Y, Dodge HH, Zhou J. Hoang B, et al. Among authors: zhou j. Alzheimers Dement. 2024 Dec;20 Suppl 10:e094211. doi: 10.1002/alz.094211. Alzheimers Dement. 2024. PMID: 39781776
55,167 results
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