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Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Randic T, Magni S, Philippidou D, Margue C, Grzyb K, Preis JR, Wroblewska JP, Nazarov PV, Mittelbronn M, Frauenknecht KBM, Skupin A, Kreis S. Randic T, et al. Among authors: mittelbronn m. Cell Rep. 2023 Jul 25;42(7):112696. doi: 10.1016/j.celrep.2023.112696. Epub 2023 Jun 29. Cell Rep. 2023. PMID: 37379213 Free article.
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D. Soriano-Baguet L, et al. Among authors: mittelbronn m. Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36848289 Free article.
Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease.
Schmit KJ, Garcia P, Sciortino A, Aho VTE, Pardo Rodriguez B, Thomas MH, Gérardy JJ, Bastero Acha I, Halder R, Cialini C, Heurtaux T, Ostahi I, Busi SB, Grandmougin L, Lowndes T, Singh Y, Martens EC, Mittelbronn M, Buttini M, Wilmes P. Schmit KJ, et al. Among authors: mittelbronn m. Cell Rep. 2023 Sep 26;42(9):113071. doi: 10.1016/j.celrep.2023.113071. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37676767 Free PMC article.
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.
Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A. Yabo YA, et al. Among authors: mittelbronn m. Genome Med. 2024 Apr 2;16(1):51. doi: 10.1186/s13073-024-01321-8. Genome Med. 2024. PMID: 38566128 Free PMC article.
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity.
Scafidi A, Lind-Holm Mogensen F, Campus E, Pailas A, Neumann K, Legrave N, Bernardin F, Pereira SL, Antony PMA, Nicot N, Mittelbronn M, Grünewald A, Nazarov PV, Poli A, Van Dyck E, Michelucci A. Scafidi A, et al. Among authors: mittelbronn m. Heliyon. 2024 Sep 11;10(18):e37792. doi: 10.1016/j.heliyon.2024.e37792. eCollection 2024 Sep 30. Heliyon. 2024. PMID: 39315158 Free PMC article.
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus.
Mgrditchian T, Brown-Clay J, Hoffmann C, Müller T, Filali L, Ockfen E, Mao X, Moreau F, Casellas CP, Kaoma T, Mittelbronn M, Thomas C. Mgrditchian T, et al. Among authors: mittelbronn m. Front Cell Dev Biol. 2023 May 15;11:1100938. doi: 10.3389/fcell.2023.1100938. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37266453 Free PMC article.
347 results