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Oxygen-Dependent Interactions between the Ruthenium Cage and the Photoreleased Inhibitor in NAMPT-Targeted Photoactivated Chemotherapy.
Abyar S, Huang L, Husiev Y, Bretin L, Chau B, Ramu V, Wildeman JH, Belfor K, Wijaya LS, van der Noord VE, Harms AC, Siegler MA, Le Dévédec SE, Bonnet S. Abyar S, et al. Among authors: bretin l. J Med Chem. 2024 Jul 11;67(13):11086-11102. doi: 10.1021/acs.jmedchem.4c00589. Epub 2024 Jun 26. J Med Chem. 2024. PMID: 38924492 Free PMC article.
In vivo metallophilic self-assembly of a light-activated anticancer drug.
Zhou XQ, Wang P, Ramu V, Zhang L, Jiang S, Li X, Abyar S, Papadopoulou P, Shao Y, Bretin L, Siegler MA, Buda F, Kros A, Fan J, Peng X, Sun W, Bonnet S. Zhou XQ, et al. Among authors: bretin l. Nat Chem. 2023 Jul;15(7):980-987. doi: 10.1038/s41557-023-01199-w. Epub 2023 May 11. Nat Chem. 2023. PMID: 37169984 Free PMC article.
Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model.
Chen Q, Cuello-Garibo JA, Bretin L, Zhang L, Ramu V, Aydar Y, Batsiun Y, Bronkhorst S, Husiev Y, Beztsinna N, Chen L, Zhou XQ, Schmidt C, Ott I, Jager MJ, Brouwer AM, Snaar-Jagalska BE, Bonnet S. Chen Q, et al. Among authors: bretin l. Chem Sci. 2022 May 16;13(23):6899-6919. doi: 10.1039/d2sc01646j. eCollection 2022 Jun 15. Chem Sci. 2022. PMID: 35774173 Free PMC article.