Shah DK - Search Results

1

Clinical validation of translational antibody PBPK model using tissue distribution data generated with ⁸⁹Zr-immuno-PET imaging.

Liu S, Li Z, Huisman M, Shah DK. Liu S, et al. Among authors: shah dk. J Pharmacokinet Pharmacodyn. 2023 Oct;50(5):377-394. doi: 10.1007/s10928-023-09869-5. Epub 2023 Jun 29. J Pharmacokinet Pharmacodyn. 2023. PMID: 37382712

2

Physiologically based pharmacokinetic model for topotecan in mice.

Shah DK, Balthasar JP. Shah DK, et al. J Pharmacokinet Pharmacodyn. 2011 Feb;38(1):121-42. doi: 10.1007/s10928-010-9181-1. Epub 2010 Nov 20. J Pharmacokinet Pharmacodyn. 2011. PMID: 21104004

3

Predicting the effects of 8C2, a monoclonal anti-topotecan antibody, on plasma and tissue disposition of topotecan.

Shah DK, Balthasar JP. Shah DK, et al. J Pharmacokinet Pharmacodyn. 2014 Feb;41(1):55-69. doi: 10.1007/s10928-013-9346-9. Epub 2013 Dec 25. J Pharmacokinet Pharmacodyn. 2014. PMID: 24368689 Free PMC article.

4

Pharmacokinetic and pharmacodynamic considerations for the next generation protein therapeutics.

Shah DK. Shah DK. J Pharmacokinet Pharmacodyn. 2015 Oct;42(5):553-71. doi: 10.1007/s10928-015-9447-8. Epub 2015 Sep 15. J Pharmacokinet Pharmacodyn. 2015. PMID: 26373957 Free PMC article. Review.

5

Influence of molecular size on tissue distribution of antibody fragments.

Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK. Li Z, et al. Among authors: shah dk. MAbs. 2016;8(1):113-9. doi: 10.1080/19420862.2015.1111497. Epub 2015 Oct 23. MAbs. 2016. PMID: 26496429 Free PMC article.

6

Quantitative characterization of in vitro bystander effect of antibody-drug conjugates.

Singh AP, Sharma S, Shah DK. Singh AP, et al. Among authors: shah dk. J Pharmacokinet Pharmacodyn. 2016 Dec;43(6):567-582. doi: 10.1007/s10928-016-9495-8. Epub 2016 Sep 26. J Pharmacokinet Pharmacodyn. 2016. PMID: 27670282 Free PMC article.

7

Influence of Molecular size on the clearance of antibody fragments.

Li Z, Krippendorff BF, Shah DK. Li Z, et al. Among authors: shah dk. Pharm Res. 2017 Oct;34(10):2131-2141. doi: 10.1007/s11095-017-2219-y. Epub 2017 Jul 5. Pharm Res. 2017. PMID: 28681164 Free PMC article.

8

Establishing in vitro-in vivo correlation for antibody drug conjugate efficacy: a PK/PD modeling approach.

Shah DK, Loganzo F, Haddish-Berhane N, Musto S, Wald HS, Barletta F, Lucas J, Clark T, Hansel S, Betts A. Shah DK, et al. J Pharmacokinet Pharmacodyn. 2018 Apr;45(2):339-349. doi: 10.1007/s10928-018-9577-x. Epub 2018 Feb 8. J Pharmacokinet Pharmacodyn. 2018. PMID: 29423862

9

Pharmacokinetics of protein and peptide conjugates.

Bumbaca B, Li Z, Shah DK. Bumbaca B, et al. Among authors: shah dk. Drug Metab Pharmacokinet. 2019 Feb;34(1):42-54. doi: 10.1016/j.dmpk.2018.11.001. Epub 2018 Nov 22. Drug Metab Pharmacokinet. 2019. PMID: 30573392 Free PMC article. Review.

10

Two-pore physiologically based pharmacokinetic model with de novo derived parameters for predicting plasma PK of different size protein therapeutics.

Li Z, Shah DK. Li Z, et al. Among authors: shah dk. J Pharmacokinet Pharmacodyn. 2019 Jun;46(3):305-318. doi: 10.1007/s10928-019-09639-2. Epub 2019 Apr 26. J Pharmacokinet Pharmacodyn. 2019. PMID: 31028591 Free PMC article.

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