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Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen MG, Deme JC, Alvarez CP, Loppnau P, Hutchinson A, Seitova A, Chandrasekaran R, Silva Ramos E, Secker C, Alqazzaz M, Wanker EE, Lea SM, Arrowsmith CH, Harding RJ. Alteen MG, et al. Among authors: chandrasekaran r. Structure. 2023 Sep 7;31(9):1121-1131.e6. doi: 10.1016/j.str.2023.06.002. Epub 2023 Jun 29. Structure. 2023. PMID: 37390814 Free PMC article.
Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles.
Yadav M, Harding RJ, Li T, Xu X, Gall-Duncan T, Khan M, Bardile CF, Sequiera GL, Duan S, Chandrasekaran R, Pan A, Bu J, Yamazaki T, Hirose T, Prinos P, Tippett L, Turner C, Curtis MA, Faull RLM, Pouladi MA, Pearson CE, He HH, Arrowsmith CH. Yadav M, et al. Among authors: chandrasekaran r. Sci Adv. 2024 Jul 19;10(29):eado5264. doi: 10.1126/sciadv.ado5264. Epub 2024 Jul 19. Sci Adv. 2024. PMID: 39028820 Free PMC article.
A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence.
Fanti R, Ayoubi R, Alende C, Fotouhi M, González Bolívar S, Chandrasekaran R, Southern K, Edwards AM, Harding RJ, Laflamme C; NeuroSGC/YCharOS/EDDU collaborative group; ABIF consortium. Fanti R, et al. Among authors: chandrasekaran r. F1000Res. 2024 Aug 13;13:922. doi: 10.12688/f1000research.153670.1. eCollection 2024. F1000Res. 2024. PMID: 39257448 Free PMC article.
253 results