Khan I - Search Results

1

Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.

Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, Whaby M, Zuberi M, Teng KW, Lefler J, Maso L, Bang I, Ostrowski MC, O'Bryan JP, Koide S. Akkapeddi P, et al. Among authors: khan i. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302485120. doi: 10.1073/pnas.2302485120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399416 Free PMC article.

2

Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo.

Khan I, Spencer-Smith R, O'Bryan JP. Khan I, et al. Oncogene. 2019 Apr;38(16):2984-2993. doi: 10.1038/s41388-018-0636-y. Epub 2018 Dec 20. Oncogene. 2019. PMID: 30573767 Free PMC article.

3

Correction: Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo.

Khan I, Spencer-Smith R, O'Bryan JP. Khan I, et al. Oncogene. 2019 May;38(22):4426. doi: 10.1038/s41388-019-0720-y. Oncogene. 2019. PMID: 30710144

4

The Promising Signatures of Circulating microRNA-145 in Epithelial Ovarian Cancer Patients.

Zuberi M, Mir R, Khan I, Javid J, Guru SA, Bhat M, Sumi MP, Ahmad I, Masroor M, Yadav P, Vishnubhatla S, Saxena A. Zuberi M, et al. Among authors: khan i. Microrna. 2020;9(1):49-57. doi: 10.2174/2211536608666190225111234. Microrna. 2020. PMID: 30799804

5

Therapeutic targeting of RAS: New hope for drugging the "undruggable".

Khan I, Rhett JM, O'Bryan JP. Khan I, et al. Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118570. doi: 10.1016/j.bbamcr.2019.118570. Epub 2019 Oct 31. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31678118 Free PMC article. Review.

6

Biology, pathology, and therapeutic targeting of RAS.

Rhett JM, Khan I, O'Bryan JP. Rhett JM, et al. Among authors: khan i. Adv Cancer Res. 2020;148:69-146. doi: 10.1016/bs.acr.2020.05.002. Epub 2020 Jul 9. Adv Cancer Res. 2020. PMID: 32723567 Free PMC article. Review.

7

Inhibition of RAS: proven and potential vulnerabilities.

Zuberi M, Khan I, O'Bryan JP. Zuberi M, et al. Among authors: khan i. Biochem Soc Trans. 2020 Oct 30;48(5):1831-1841. doi: 10.1042/BST20190023. Biochem Soc Trans. 2020. PMID: 32869838 Free PMC article. Review.

8

Epigenetic Silencing of DAPK1and p16 ^INK4a Genes by CpG Island Hypermethylation in Epithelial Ovarian Cancer Patients.

Zuberi M, Dholariya S, Khan I, Mir R, Guru S, Bhat M, Sumi M, Saxena A. Zuberi M, et al. Among authors: khan i. Indian J Clin Biochem. 2021 Apr;36(2):200-207. doi: 10.1007/s12291-020-00888-4. Epub 2020 May 16. Indian J Clin Biochem. 2021. PMID: 33867711 Free PMC article.

9

Targeting the KRAS α4-α5 allosteric interface inhibits pancreatic cancer tumorigenesis.

Khan I, Marelia-Bennet C, Lefler J, Zuberi M, Denbaum E, Koide A, Connor DM, Broome AM, Pécot T, Timmers C, Ostrowski MC, Koide S, O'Bryan JP. Khan I, et al. Small GTPases. 2022 Jan;13(1):114-127. doi: 10.1080/21541248.2021.1906621. Epub 2021 May 5. Small GTPases. 2022. PMID: 33949915 Free PMC article.

10

Probing RAS Function with Monobodies.

Khan I, O'Bryan JP. Khan I, et al. Methods Mol Biol. 2021;2262:281-302. doi: 10.1007/978-1-0716-1190-6_17. Methods Mol Biol. 2021. PMID: 33977484 Free PMC article.

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