A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies.
Gilormini PA, Thota VN, Fers-Lidou A, Ashmus RA, Nodwell M, Brockerman J, Kuo CW, Wang Y, Gray TE, Nitin, McDonagh AW, Guu SY, Ertunc N, Yeo D, Zandberg WF, Khoo KH, Britton R, Vocadlo DJ.
Gilormini PA, et al. Among authors: khoo kh.
Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2314026121. doi: 10.1073/pnas.2314026121. Epub 2024 Jun 25.
Proc Natl Acad Sci U S A. 2024.
PMID: 38917011