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Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition.
Nath K, Gupta PK, Basappa J, Wang S, Sen N, Lobello C, Tomar JS, Shestov AA, Orlovskiy S, Arias-Mendoza F, Rauert-Wunderlich H, Nelson DS, Glickson JD, Wasik MA. Nath K, et al. Among authors: glickson jd. J Transl Med. 2024 Jul 4;22(1):622. doi: 10.1186/s12967-024-05371-9. J Transl Med. 2024. PMID: 38965536 Free PMC article.
Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function.
Zhang Q, Basappa J, Wang HY, Nunez-Cruz S, Lobello C, Wang S, Liu X, Chekol S, Guo L, Ziober A, Nejati R, Shestov A, Feldman M, Glickson JD, Turner SD, Blair IA, Van Dang C, Wasik MA. Zhang Q, et al. Among authors: glickson jd. Leukemia. 2023 Dec;37(12):2436-2447. doi: 10.1038/s41375-023-02038-0. Epub 2023 Sep 29. Leukemia. 2023. PMID: 37773266 Free PMC article.
Coherence pathway analysis of J-coupled lipids and lactate and effective suppression of lipids upon the selective multiple quantum coherence lactate editing sequence.
Lee SC, Hariharan H, Arias-Mendoza F, Mizsei G, Nath K, Chawla S, Elliott MA, Reddy R, Glickson JD. Lee SC, et al. Among authors: glickson jd. Biomed Phys Eng Express. 2022 Mar 8;8(3):10.1088/2057-1976/ac57ad. doi: 10.1088/2057-1976/ac57ad. Biomed Phys Eng Express. 2022. PMID: 35193126 Free PMC article.
Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.
Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, Blair IA, Glickson JD, Wasik MA. Lee SC, et al. Among authors: glickson jd. Mol Cancer Res. 2019 Jun;17(6):1365-1377. doi: 10.1158/1541-7786.MCR-18-0256. Epub 2019 Mar 12. Mol Cancer Res. 2019. PMID: 30862686 Free PMC article.
203 results