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Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.
Herder V, Dee K, Wojtus JK, Epifano I, Goldfarb D, Rozario C, Gu Q, Da Silva Filipe A, Nomikou K, Nichols J, Jarrett RF, Stevenson A, McFarlane S, Stewart ME, Szemiel AM, Pinto RM, Masdefiol Garriga A, Davis C, Allan J, Graham SV, Murcia PR, Boutell C. Herder V, et al. Among authors: gu q. PLoS Biol. 2021 Dec 21;19(12):e3001065. doi: 10.1371/journal.pbio.3001065. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34932557 Free PMC article.
The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection.
Hardy A, Bakshi S, Furnon W, MacLean O, Gu Q, Varjak M, Varela M, Aziz MA, Shaw AE, Pinto RM, Cameron Ruiz N, Mullan C, Taggart AE, Da Silva Filipe A, Randall RE, Wilson SJ, Stewart ME, Palmarini M. Hardy A, et al. Among authors: gu q. mBio. 2023 Jun 27;14(3):e0010123. doi: 10.1128/mbio.00101-23. Epub 2023 Apr 25. mBio. 2023. PMID: 37097030 Free PMC article.
Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning.
Meehan GR, Herder V, Allan J, Huang X, Kerr K, Mendonca DC, Ilia G, Wright DW, Nomikou K, Gu Q, Molina Arias S, Hansmann F, Hardas A, Attipa C, De Lorenzo G, Cowton V, Upfold N, Palmalux N, Brown JC, Barclay WS, Filipe ADS, Furnon W, Patel AH, Palmarini M. Meehan GR, et al. Among authors: gu q. PLoS Pathog. 2023 Nov 7;19(11):e1011589. doi: 10.1371/journal.ppat.1011589. eCollection 2023 Nov. PLoS Pathog. 2023. PMID: 37934791 Free PMC article.
Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination.
Baksmeier C, Blundell P, Steckel J, Schultz V, Gu Q, Da Silva Filipe A, Kohl A, Linnington C, Lu D, Dell A, Haslam S, Wang J, Czajkowsky D, Goebels N, Pleass RJ. Baksmeier C, et al. Among authors: gu q. Immunology. 2021 Sep;164(1):90-105. doi: 10.1111/imm.13341. Epub 2021 May 9. Immunology. 2021. PMID: 33880776 Free PMC article.
3,746 results