Mitra MS - Search Results

1

Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases.

Yadav R, Sukumaran S, Lutman J, Mitra MS, Halpern W, Sun T, Setiadi AF, Neighbors M, Sheng XR, Yip V, Shen BQ, Liu C, Han L, Ovacik AM, Wu Y, Glickstein S, Kunder R, Arron JR, Pan L, Kamath AV, Stefanich EG. Yadav R, et al. Among authors: mitra ms. J Pharm Sci. 2023 Nov;112(11):2910-2920. doi: 10.1016/j.xphs.2023.07.005. Epub 2023 Jul 8. J Pharm Sci. 2023. PMID: 37429356 Free article.

2

Translational and pharmacokinetic-pharmacodynamic application for the clinical development of GDC-0334, a novel TRPA1 inhibitor.

Chan P, Ding HT, Liederer BM, Mao J, Belloni P, Chen L, Gao SS, Joseph V, Yang X, Lin JS, Mitra MS, Putnam WS, Quartino A, Bauer RN, Pan L. Chan P, et al. Among authors: mitra ms. Clin Transl Sci. 2021 Sep;14(5):1945-1954. doi: 10.1111/cts.13049. Epub 2021 May 31. Clin Transl Sci. 2021. PMID: 34058071 Free PMC article. Clinical Trial.

3

A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys.

Mitra MS, Lancaster K, Adedeji AO, Palanisamy GS, Dave RA, Zhong F, Holdren MS, Turley SJ, Liang WC, Wu Y, Meng YG, Vernes JM, Schutten MM. Mitra MS, et al. Toxicol Sci. 2020 May 1;175(1):24-34. doi: 10.1093/toxsci/kfaa024. Toxicol Sci. 2020. PMID: 32077954

4

Harmonized 3Rs-based non-mutagenic impurity qualification study designs developed using the results of an IQ consortium survey.

Mitra MS, Datta K, Hutchinson R, Nicolette JJ, Pettersen JC, Wegesser TC, Bercu JP. Mitra MS, et al. Regul Toxicol Pharmacol. 2021 Jun;122:104895. doi: 10.1016/j.yrtph.2021.104895. Epub 2021 Feb 19. Regul Toxicol Pharmacol. 2021. PMID: 33610610

5

Foreign Body Reaction, Retinal Degeneration, and Epiretinal Membranes Associated With Intravitreal Administration of PLGA Rods.

Booler H, Larsen T, Shelton A, Bansteev V, Mitra MS. Booler H, et al. Among authors: mitra ms. Toxicol Pathol. 2021 Apr;49(3):656-662. doi: 10.1177/0192623320948851. Epub 2020 Sep 25. Toxicol Pathol. 2021. PMID: 32975492

6

Development of peptide therapeutics: A nonclinical safety assessment perspective.

Mitra MS, DeMarco S, Holub B, Thiruneelakantapillai L, Thackaberry EA. Mitra MS, et al. Regul Toxicol Pharmacol. 2020 Nov;117:104766. doi: 10.1016/j.yrtph.2020.104766. Epub 2020 Aug 19. Regul Toxicol Pharmacol. 2020. PMID: 32827570

7

Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice.

Schweitzer GG, Chen Z, Gan C, McCommis KS, Soufi N, Chrast R, Mitra MS, Yang K, Gross RW, Finck BN. Schweitzer GG, et al. Among authors: mitra ms. J Lipid Res. 2015 Apr;56(4):848-58. doi: 10.1194/jlr.M055962. Epub 2015 Feb 26. J Lipid Res. 2015. PMID: 25722343 Free PMC article.

8

Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice.

Hu M, Yin H, Mitra MS, Liang X, Ajmo JM, Nadra K, Chrast R, Finck BN, You M. Hu M, et al. Among authors: mitra ms. Hepatology. 2013 Dec;58(6):1953-63. doi: 10.1002/hep.26589. Epub 2013 Oct 17. Hepatology. 2013. PMID: 23787969 Free PMC article.

9

Note: Neutron shutter for Kolkata superconducting cyclotron.

Pal G, Bandopadhyay T, Nandi C, Chatterjee S, Ravishankar R, Bhattacharya S, Mitra MS, Akhter J, Mishra S. Pal G, et al. Among authors: mitra ms. Rev Sci Instrum. 2013 May;84(5):056111. doi: 10.1063/1.4807705. Rev Sci Instrum. 2013. PMID: 23742609

10

Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation.

Mitra MS, Chen Z, Ren H, Harris TE, Chambers KT, Hall AM, Nadra K, Klein S, Chrast R, Su X, Morris AJ, Finck BN. Mitra MS, et al. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):642-7. doi: 10.1073/pnas.1213493110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267081 Free PMC article.

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