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Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes.
Jacobsen LM, Diggins K, Blanchfield L, McNichols J, Perry DJ, Brant J, Dong X, Bacher R, Gersuk VH, Schatz DA, Atkinson MA, Mathews CE, Haller MJ, Long SA, Linsley PS, Brusko TM. Jacobsen LM, et al. Among authors: gersuk vh. JCI Insight. 2023 Aug 22;8(16):e161812. doi: 10.1172/jci.insight.161812. JCI Insight. 2023. PMID: 37432736 Free PMC article.
A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma.
Khaenam P, Rinchai D, Altman MC, Chiche L, Buddhisa S, Kewcharoenwong C, Suwannasaen D, Mason M, Whalen E, Presnell S, Susaengrat W, O'Brien K, Nguyen QA, Gersuk V, Linsley PS, Lertmemongkolchai G, Chaussabel D. Khaenam P, et al. J Transl Med. 2014 Mar 11;12:65. doi: 10.1186/1479-5876-12-65. J Transl Med. 2014. PMID: 24612859 Free PMC article.
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS. Cerosaletti K, et al. Among authors: gersuk vh. J Immunol. 2017 Jul 1;199(1):323-335. doi: 10.4049/jimmunol.1700172. Epub 2017 May 31. J Immunol. 2017. PMID: 28566371 Free PMC article.
A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders.
Wambre E, Bajzik V, DeLong JH, O'Brien K, Nguyen QA, Speake C, Gersuk VH, DeBerg HA, Whalen E, Ni C, Farrington M, Jeong D, Robinson D, Linsley PS, Vickery BP, Kwok WW. Wambre E, et al. Among authors: gersuk vh. Sci Transl Med. 2017 Aug 2;9(401):eaam9171. doi: 10.1126/scitranslmed.aam9171. Sci Transl Med. 2017. PMID: 28768806 Free PMC article. Clinical Trial.
Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.
DeBerg HA, Zaidi MB, Altman MC, Khaenam P, Gersuk VH, Campos FD, Perez-Martinez I, Meza-Segura M, Chaussabel D, Banchereau J, Estrada-Garcia T, Linsley PS. DeBerg HA, et al. Among authors: gersuk vh. PLoS One. 2018 Jan 29;13(1):e0192082. doi: 10.1371/journal.pone.0192082. eCollection 2018. PLoS One. 2018. PMID: 29377961 Free PMC article.
Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy.
Sheih A, Voillet V, Hanafi LA, DeBerg HA, Yajima M, Hawkins R, Gersuk V, Riddell SR, Maloney DG, Wohlfahrt ME, Pande D, Enstrom MR, Kiem HP, Adair JE, Gottardo R, Linsley PS, Turtle CJ. Sheih A, et al. Nat Commun. 2020 Jan 10;11(1):219. doi: 10.1038/s41467-019-13880-1. Nat Commun. 2020. PMID: 31924795 Free PMC article. Clinical Trial.
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.
Arnett A, Moo KG, Flynn KJ, Sundberg TB, Johannessen L, Shamji AF, Gray NS, Decker T, Zheng Y, Gersuk VH, Rahman ZS, Levy DE, Marié IJ, Linsley PS, Xavier RJ, Khor B. Arnett A, et al. Among authors: gersuk vh. Mol Cell Biol. 2021 Aug 24;41(9):e0008521. doi: 10.1128/MCB.00085-21. Epub 2021 Aug 24. Mol Cell Biol. 2021. PMID: 34124936 Free PMC article.
Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.
Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco MG, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, Speake C, Greenbaum CJ, Nepom GT, Cerosaletti K. Linsley PS, et al. Among authors: gersuk vh. JCI Insight. 2021 Nov 22;6(22):e151349. doi: 10.1172/jci.insight.151349. JCI Insight. 2021. PMID: 34806648 Free PMC article.
46 results