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Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer.
Minohara K, Imai M, Matoba T, Wing JB, Shime H, Odanaka M, Uraki R, Kawakita D, Toyama T, Takahashi S, Morita A, Murakami S, Ohkura N, Sakaguchi S, Iwasaki S, Yamazaki S. Minohara K, et al. Among authors: sakaguchi s. Cancer Sci. 2023 Apr;114(4):1256-1269. doi: 10.1111/cas.15698. Epub 2023 Jan 23. Cancer Sci. 2023. PMID: 36529525 Free PMC article.
Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases.
Yasumizu Y, Takeuchi D, Morimoto R, Takeshima Y, Okuno T, Kinoshita M, Morita T, Kato Y, Wang M, Motooka D, Okuzaki D, Nakamura Y, Mikami N, Arai M, Zhang X, Kumanogoh A, Mochizuki H, Ohkura N, Sakaguchi S. Yasumizu Y, et al. Among authors: sakaguchi s. Cell Genom. 2024 Feb 14;4(2):100473. doi: 10.1016/j.xgen.2023.100473. Epub 2024 Jan 3. Cell Genom. 2024. PMID: 38359792 Free PMC article.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H. Mori S, et al. Among authors: sakaguchi s. Cell. 2024 Oct 17;187(21):6071-6087.e20. doi: 10.1016/j.cell.2024.08.025. Epub 2024 Sep 13. Cell. 2024. PMID: 39276775
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation.
Morikawa H, Ohkura N, Vandenbon A, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Standley DM, Date H, Sakaguchi S; FANTOM Consortium. Morikawa H, et al. Among authors: sakaguchi s. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5289-94. doi: 10.1073/pnas.1312717110. Epub 2014 Mar 27. Proc Natl Acad Sci U S A. 2014. PMID: 24706905 Free PMC article.
Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells.
Baßler K, Schmidleithner L, Shakiba MH, Elmzzahi T, Köhne M, Floess S, Scholz R, Ohkura N, Sadlon T, Klee K, Neubauer A, Sakaguchi S, Barry SC, Huehn J, Bonaguro L, Ulas T, Beyer M. Baßler K, et al. Among authors: sakaguchi s. Front Immunol. 2023 Jul 25;14:1107397. doi: 10.3389/fimmu.2023.1107397. eCollection 2023. Front Immunol. 2023. PMID: 37559728 Free PMC article.
1,222 results