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Page 1
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5.
Brusa I, Sondo E, Pesce E, Tomati V, Gioia D, Falchi F, Balboni B, Ortega Martínez JA, Veronesi M, Romeo E, Margaroli N, Recanatini M, Girotto S, Pedemonte N, Roberti M, Cavalli A. Brusa I, et al. Among authors: balboni b. J Med Chem. 2023 Jul 27;66(14):9797-9822. doi: 10.1021/acs.jmedchem.3c00608. Epub 2023 Jul 13. J Med Chem. 2023. PMID: 37440686 Free PMC article.
ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders.
Demuro S, Sauvey C, Tripathi SK, Di Martino RMC, Shi D, Ortega JA, Russo D, Balboni B, Giabbai B, Storici P, Girotto S, Abagyan R, Cavalli A. Demuro S, et al. Among authors: balboni b. Eur J Med Chem. 2022 Feb 5;229:114054. doi: 10.1016/j.ejmech.2021.114054. Epub 2021 Dec 16. Eur J Med Chem. 2022. PMID: 34959172 Free PMC article.
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives.
Barbieri F, Bosio AG, Pattarozzi A, Tonelli M, Bajetto A, Verduci I, Cianci F, Cannavale G, Palloni LMG, Francesconi V, Thellung S, Fiaschi P, Mazzetti S, Schenone S, Balboni B, Girotto S, Malatesta P, Daga A, Zona G, Mazzanti M, Florio T. Barbieri F, et al. Among authors: balboni b. J Exp Clin Cancer Res. 2022 Feb 8;41(1):53. doi: 10.1186/s13046-021-02213-0. J Exp Clin Cancer Res. 2022. PMID: 35135603 Free PMC article.
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry.
Bagnolini G, Balboni B, Schipani F, Gioia D, Veronesi M, De Franco F, Kaya C, Jumde RP, Ortega JA, Girotto S, Hirsch AKH, Roberti M, Cavalli A. Bagnolini G, et al. Among authors: balboni b. ACS Med Chem Lett. 2022 Jul 28;13(8):1262-1269. doi: 10.1021/acsmedchemlett.2c00063. eCollection 2022 Aug 11. ACS Med Chem Lett. 2022. PMID: 35978685 Free PMC article.
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer.
Rinaldi F, Schipani F, Balboni B, Catalano F, Marotta R, Myers SH, Previtali V, Veronesi M, Scietti L, Cecatiello V, Pasqualato S, Ortega JA, Girotto S, Cavalli A. Rinaldi F, et al. Among authors: balboni b. Angew Chem Int Ed Engl. 2023 Dec 18;62(51):e202312517. doi: 10.1002/anie.202312517. Epub 2023 Nov 20. Angew Chem Int Ed Engl. 2023. PMID: 37924230
16 results