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249 results

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Targeting the Alternative Complement Pathway With Iptacopan to Treat IgA Nephropathy: Design and Rationale of the APPLAUSE-IgAN Study.
Rizk DV, Rovin BH, Zhang H, Kashihara N, Maes B, Trimarchi H, Perkovic V, Meier M, Kollins D, Papachristofi O, Charney A, Barratt J. Rizk DV, et al. Among authors: charney a. Kidney Int Rep. 2023 Feb 9;8(5):968-979. doi: 10.1016/j.ekir.2023.01.041. eCollection 2023 May. Kidney Int Rep. 2023. PMID: 37180505 Free PMC article.
Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy.
Zhang H, Rizk DV, Perkovic V, Maes B, Kashihara N, Rovin B, Trimarchi H, Sprangers B, Meier M, Kollins D, Papachristofi O, Milojevic J, Junge G, Nidamarthy PK, Charney A, Barratt J. Zhang H, et al. Among authors: charney a. Kidney Int. 2024 Jan;105(1):189-199. doi: 10.1016/j.kint.2023.09.027. Epub 2023 Oct 31. Kidney Int. 2024. PMID: 37914086 Free article. Clinical Trial.
2024 Update of the RECOVER-Adult Long COVID Research Index.
Geng LN, Erlandson KM, Hornig M, Letts R, Selvaggi C, Ashktorab H, Atieh O, Bartram L, Brim H, Brosnahan SB, Brown J, Castro M, Charney A, Chen P, Deeks SG, Erdmann N, Flaherman VJ, Ghamloush MA, Goepfert P, Goldman JD, Han JE, Hess R, Hirshberg E, Hoover SE, Katz SD, Kelly JD, Klein JD, Krishnan JA, Lee-Iannotti J, Levitan EB, Marconi VC, Metz TD, Modes ME, Nikolich JŽ, Novak RM, Ofotokun I, Okumura MJ, Parthasarathy S, Patterson TF, Peluso MJ, Poppas A, Quintero Cardona O, Scott J, Shellito J, Sherif ZA, Singer NG, Taylor BS, Thaweethai T, Verduzco-Gutierrez M, Wisnivesky J, McComsey GA, Horwitz LI, Foulkes AS; RECOVER Consortium. Geng LN, et al. Among authors: charney a. JAMA. 2024 Dec 18. doi: 10.1001/jama.2024.24184. Online ahead of print. JAMA. 2024. PMID: 39693079
Large Language Models and Empathy: Systematic Review.
Sorin V, Brin D, Barash Y, Konen E, Charney A, Nadkarni G, Klang E. Sorin V, et al. Among authors: charney a. J Med Internet Res. 2024 Dec 11;26:e52597. doi: 10.2196/52597. J Med Internet Res. 2024. PMID: 39661968 Free article. Review.
Extracting International Classification of Diseases Codes from Clinical Documentation using Large Language Models.
Simmons A, Takkavatakarn K, McDougal M, Dilcher B, Pincavitch J, Meadows L, Kauffman J, Klang E, Wig R, Smith GS, Soroush A, Freeman R, Apakama D, Charney A, Kohli-Seth R, Nadkarni G, Sakhuja A. Simmons A, et al. Among authors: charney a. Appl Clin Inform. 2024 Nov 28. doi: 10.1055/a-2491-3872. Online ahead of print. Appl Clin Inform. 2024. PMID: 39608761
Disagreements in Medical Ethics Question Answering Between Large Language Models and Physicians.
Soffer S, Nesselroth D, Pragier K, Anteby R, Apakama D, Holmes E, Sawant AS, Abbott E, Lepow LA, Vasudev I, Lampert J, Gendler M, Horesh N, Efros O, Glicksberg BS, Freeman R, Reich DL, Charney AW, Nadkarni GN, Klang E. Soffer S, et al. Among authors: charney aw. Res Sq [Preprint]. 2024 Nov 15:rs.3.rs-5382879. doi: 10.21203/rs.3.rs-5382879/v1. Res Sq. 2024. PMID: 39606472 Free PMC article. Preprint.
Benchmarking Large Language Models for Extraction of International Classification of Diseases Codes from Clinical Documentation.
Simmons A, Takkavatakarn K, McDougal M, Dilcher B, Pincavitch J, Meadows L, Kauffman J, Klang E, Wig R, Smith G, Soroush A, Freeman R, Apakama DJ, Charney AW, Kohli-Seth R, Nadkarni GN, Sakhuja A. Simmons A, et al. Among authors: charney aw. medRxiv [Preprint]. 2024 Nov 23:2024.04.29.24306573. doi: 10.1101/2024.04.29.24306573. medRxiv. 2024. Update in: Appl Clin Inform. 2024 Nov 28. doi: 10.1055/a-2491-3872 PMID: 39606395 Free PMC article. Updated. Preprint.
Intravenous administration of blood-brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system.
Wang C, Wang S, Xue Y, Zhong Y, Li H, Hou X, Kang DD, Liu Z, Tian M, Wang L, Cao D, Yu Y, Liu J, Cheng X, Markovic T, Hashemi A, Kopell BH, Charney AW, Nestler EJ, Dong Y. Wang C, et al. Among authors: charney aw. Nat Biotechnol. 2024 Nov 25. doi: 10.1038/s41587-024-02487-7. Online ahead of print. Nat Biotechnol. 2024. PMID: 39587229
249 results