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Page 1
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex.
Strickson S, Houslay KF, Negri VA, Ohne Y, Ottosson T, Dodd RB, Huntington CC, Baker T, Li J, Stephenson KE, O'Connor AJ, Sagawe JS, Killick H, Moore T, Rees DG, Koch S, Sanden C, Wang Y, Gubbins E, Ghaedi M, Kolbeck R, Saumyaa S, Erjefält JS, Sims GP, Humbles AA, Scott IC, Romero Ros X, Cohen ES. Strickson S, et al. Among authors: kolbeck r. Eur Respir J. 2023 Sep 28;62(3):2202210. doi: 10.1183/13993003.02210-2022. Print 2023 Sep. Eur Respir J. 2023. PMID: 37442582 Free PMC article.
Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD.
Dagher R, Fogel P, Wang J, Soussan D, Chiang CC, Kearley J, Muthas D, Taillé C, Berger P, Bourdin A, Chenivesse C, Leroy S, Anderson G, Humbles AA, Aubier M, Kolbeck R, Pretolani M; COBRA Consortium. Dagher R, et al. Among authors: kolbeck r. PLoS One. 2022 Dec 8;17(12):e0277357. doi: 10.1371/journal.pone.0277357. eCollection 2022. PLoS One. 2022. PMID: 36480517 Free PMC article.
Inhalation of SP-101 Followed by Inhaled Doxorubicin Results in Robust and Durable hCFTRΔR Transgene Expression in the Airways of Wild-Type and Cystic Fibrosis Ferrets.
Excoffon KJDA, Smith MD, Falese L, Schulingkamp R, Lin S, Mahankali M, Narayan PKL, Glatfelter MR, Limberis MP, Yuen E, Kolbeck R. Excoffon KJDA, et al. Among authors: kolbeck r. Hum Gene Ther. 2024 Sep;35(17-18):710-725. doi: 10.1089/hum.2024.064. Epub 2024 Sep 4. Hum Gene Ther. 2024. PMID: 39155828
SP-101, A Novel Adeno-Associated Virus Gene Therapy for the Treatment of Cystic Fibrosis, Mediates Functional Correction of Primary Human Airway Epithelia From Donors with Cystic Fibrosis.
Excoffon KJDA, Lin S, Narayan PKL, Sitaraman S, Jimah AM, Fallon TT, James ML, Glatfelter MR, Limberis MP, Smith MD, Guffanti G, Kolbeck R. Excoffon KJDA, et al. Among authors: kolbeck r. Hum Gene Ther. 2024 Sep;35(17-18):695-709. doi: 10.1089/hum.2024.063. Epub 2024 Aug 29. Hum Gene Ther. 2024. PMID: 39155805
Durable transgene expression and efficient re-administration after rAAV2.5T-mediated fCFTRΔR gene delivery to adult ferret lungs.
Tang Y, Ebadi M, Lei J, Feng Z, Fakhari S, Wu P, Smith MD, Limberis MP, Kolbeck R, Excoffon KJ, Yan Z, Engelhardt JF. Tang Y, et al. Among authors: kolbeck r. Mol Ther Methods Clin Dev. 2024 Mar 28;32(2):101244. doi: 10.1016/j.omtm.2024.101244. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38638546 Free PMC article.
Immunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungs.
Tang Y, Fakhari S, Huntemann ED, Feng Z, Wu P, Feng WY, Lei J, Yuan F, Excoffon KJ, Wang K, Limberis MP, Kolbeck R, Yan Z, Engelhardt JF. Tang Y, et al. Among authors: kolbeck r. Mol Ther Methods Clin Dev. 2023 Mar 2;29:70-80. doi: 10.1016/j.omtm.2023.02.015. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 36950451 Free PMC article.
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M.
Botelho F, Dubey A, Ayaub EA, Park R, Yip A, Humbles A, Kolbeck R, Richards CD. Botelho F, et al. Among authors: kolbeck r. Mediators Inflamm. 2020 Nov 28;2020:4087315. doi: 10.1155/2020/4087315. eCollection 2020. Mediators Inflamm. 2020. PMID: 33376451 Free PMC article.
145 results