Meyer UA - Search Results

1

Debrisoquine/sparteine-type polymorphism of drug oxidation. Purification and characterization of two functionally different human liver cytochrome P-450 isozymes involved in impaired hydroxylation of the prototype substrate bufuralol.

Gut J, Catin T, Dayer P, Kronbach T, Zanger U, Meyer UA. Gut J, et al. Among authors: meyer ua. J Biol Chem. 1986 Sep 5;261(25):11734-43. J Biol Chem. 1986. PMID: 3745165 Free article.

2

The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.

Meyer UA, Gut J, Kronbach T, Skoda C, Meier UT, Catin T, Dayer P. Meyer UA, et al. Xenobiotica. 1986 May;16(5):449-64. doi: 10.3109/00498258609050251. Xenobiotica. 1986. PMID: 2874666

3

Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency.

Dayer P, Kronbach T, Eichelbaum M, Meyer UA. Dayer P, et al. Among authors: meyer ua. Biochem Pharmacol. 1987 Dec 1;36(23):4145-52. doi: 10.1016/0006-2952(87)90573-9. Biochem Pharmacol. 1987. PMID: 3689440

4

Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P450 isozyme with high activity for bufuralol hydroxylation.

Gut J, Gasser R, Dayer P, Kronbach T, Catin T, Meyer UA. Gut J, et al. Among authors: meyer ua. FEBS Lett. 1984 Aug 6;173(2):287-90. doi: 10.1016/0014-5793(84)80792-9. FEBS Lett. 1984. PMID: 6146537 Free article.

5

Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism)--increased Michaelis is Constant (Km) and loss of stereoselectivity of bufuralol 1'-hydroxylation in poor metabolizers.

Dayer P, Gasser R, Gut J, Kronbach T, Robertz GM, Eichelbaum M, Meyer UA. Dayer P, et al. Among authors: meyer ua. Biochem Biophys Res Commun. 1984 Nov 30;125(1):374-80. doi: 10.1016/s0006-291x(84)80378-2. Biochem Biophys Res Commun. 1984. PMID: 6508804

6

Sequence requirements for cytochrome P-450IID1 catalytic activity. A single amino acid change (Ile380 Phe) specifically decreases Vmax of the enzyme for bufuralol but not debrisoquine hydroxylation.

Matsunaga E, Zeugin T, Zanger UM, Aoyama T, Meyer UA, Gonzalez FJ. Matsunaga E, et al. Among authors: meyer ua. J Biol Chem. 1990 Oct 5;265(28):17197-201. J Biol Chem. 1990. PMID: 1976628 Free article.

7

The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.

Meyer UA, Skoda RC, Zanger UM. Meyer UA, et al. Pharmacol Ther. 1990;46(2):297-308. doi: 10.1016/0163-7258(90)90096-k. Pharmacol Ther. 1990. PMID: 2181495 Review.

8

Stereo- and regioselectivity of hepatic oxidation in man--effect of the debrisoquine/sparteine phenotype on bufuralol hydroxylation.

Dayer P, Leemann T, Küpfer A, Kronbach T, Meyer UA. Dayer P, et al. Among authors: meyer ua. Eur J Clin Pharmacol. 1986;31(3):313-8. doi: 10.1007/BF00981130. Eur J Clin Pharmacol. 1986. PMID: 2878813

9

In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone.

Kroemer HK, Mikus G, Kronbach T, Meyer UA, Eichelbaum M. Kroemer HK, et al. Among authors: meyer ua. Clin Pharmacol Ther. 1989 Jan;45(1):28-33. doi: 10.1038/clpt.1989.5. Clin Pharmacol Ther. 1989. PMID: 2910635

10

Mephenytoin-type polymorphism of drug oxidation: purification and characterization of a human liver cytochrome P-450 isozyme catalyzing microsomal mephenytoin hydroxylation.

Gut J, Meier UT, Catin T, Meyer UA. Gut J, et al. Among authors: meyer ua. Biochim Biophys Acta. 1986 Dec 10;884(3):435-47. doi: 10.1016/0304-4165(86)90194-7. Biochim Biophys Acta. 1986. PMID: 3096378

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

356 results

Search Page

Filters