Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection.
Byrnes AE, Dominguez SL, Yen CW, Laufer BI, Foreman O, Reichelt M, Lin H, Sagolla M, Hötzel K, Ngu H, Soendergaard C, Estevez A, Lin HC, Goyon A, Bian J, Lin J, Hinz FI, Friedman BA, Easton A, Hoogenraad CC.
Byrnes AE, et al. Among authors: goyon a.
Mol Ther Nucleic Acids. 2023 May 9;32:773-793. doi: 10.1016/j.omtn.2023.05.005. eCollection 2023 Jun 13.
Mol Ther Nucleic Acids. 2023.
PMID: 37346977
Free PMC article.