Dual role of cofilin in APP trafficking and amyloid-β clearance.
Liu T, Woo JA, Yan Y, LePochat P, Bukhari MZ, Kang DE.
Liu T, et al.
FASEB J. 2019 Dec;33(12):14234-14247. doi: 10.1096/fj.201901268R. Epub 2019 Oct 24.
FASEB J. 2019.
PMID: 31646885
Free PMC article.
These results taken together indicate a significant role for cofilin in Abeta accumulation via dual and opposing endocytic mechanisms of promoting Abeta production in neurons and inhibiting Abeta clearance in microglia.-Liu, T., Woo, J.-A. A., Yan, Y., LePochat, P., …
These results taken together indicate a significant role for cofilin in Abeta accumulation via dual and opposing endocytic mechanisms of pro …