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Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.
Ferruzzi J, Murtada SI, Li G, Jiao Y, Uman S, Ting MY, Tellides G, Humphrey JD. Ferruzzi J, et al. Among authors: humphrey jd. Arterioscler Thromb Vasc Biol. 2016 May;36(5):919-27. doi: 10.1161/ATVBAHA.116.307436. Epub 2016 Mar 17. Arterioscler Thromb Vasc Biol. 2016. PMID: 26988590 Free PMC article.
mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.
Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G. Jiao Y, et al. Among authors: humphrey jd. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1657-1666. doi: 10.1161/ATVBAHA.117.309653. Epub 2017 Jul 27. Arterioscler Thromb Vasc Biol. 2017. PMID: 28751568 Free PMC article.
Mechanics-driven mechanobiological mechanisms of arterial tortuosity.
Weiss D, Cavinato C, Gray A, Ramachandra AB, Avril S, Humphrey JD, Latorre M. Weiss D, et al. Among authors: humphrey jd. Sci Adv. 2020 Dec 4;6(49):eabd3574. doi: 10.1126/sciadv.abd3574. Print 2020 Dec. Sci Adv. 2020. PMID: 33277255 Free PMC article.
Developmental origins of mechanical homeostasis in the aorta.
Murtada SI, Kawamura Y, Li G, Schwartz MA, Tellides G, Humphrey JD. Murtada SI, et al. Among authors: humphrey jd. Dev Dyn. 2021 May;250(5):629-639. doi: 10.1002/dvdy.283. Epub 2021 Jan 4. Dev Dyn. 2021. PMID: 33341996 Free PMC article.
Differential propensity of dissection along the aorta.
Ban E, Cavinato C, Humphrey JD. Ban E, et al. Among authors: humphrey jd. Biomech Model Mechanobiol. 2021 Jun;20(3):895-907. doi: 10.1007/s10237-021-01418-8. Epub 2021 Jan 19. Biomech Model Mechanobiol. 2021. PMID: 33464476 Free PMC article.
404 results