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Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled homologous recombination.
Davó-Martínez C, Helfricht A, Ribeiro-Silva C, Raams A, Tresini M, Uruci S, van Cappellen WA, Taneja N, Demmers JAA, Pines A, Theil AF, Vermeulen W, Lans H. Davó-Martínez C, et al. Among authors: demmers jaa. Nucleic Acids Res. 2023 Sep 22;51(17):9055-9074. doi: 10.1093/nar/gkad609. Nucleic Acids Res. 2023. PMID: 37470997 Free PMC article.
The core spliceosome as target and effector of non-canonical ATM signalling.
Tresini M, Warmerdam DO, Kolovos P, Snijder L, Vrouwe MG, Demmers JA, van IJcken WF, Grosveld FG, Medema RH, Hoeijmakers JH, Mullenders LH, Vermeulen W, Marteijn JA. Tresini M, et al. Nature. 2015 Jul 2;523(7558):53-8. doi: 10.1038/nature14512. Epub 2015 Jun 24. Nature. 2015. PMID: 26106861 Free PMC article.
Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA.
Saha C, Mohanraju P, Stubbs A, Dugar G, Hoogstrate Y, Kremers GJ, van Cappellen WA, Horst-Kreft D, Laffeber C, Lebbink JHG, Bruens S, Gaskin D, Beerens D, Klunder M, Joosten R, Demmers JAA, van Gent D, Mouton JW, van der Spek PJ, van der Oost J, van Baarlen P, Louwen R. Saha C, et al. Among authors: demmers jaa. Sci Adv. 2020 Jun 17;6(25):eaaz4849. doi: 10.1126/sciadv.aaz4849. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32596446 Free PMC article.
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Among authors: demmers jaa. Nat Cell Biol. 2021 Jun;23(6):608-619. doi: 10.1038/s41556-021-00692-z. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108662 Free PMC article.
Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.
Geijer ME, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, Cugusi S, van Toorn M, van der Woude M, Janssens RC, Kok YP, Gong W, Raams A, Lo CSY, Lebbink JHG, Geverts B, Plummer DA, Bezstarosti K, Theil AF, Mitter R, Houtsmuller AB, Vermeulen W, Demmers JAA, Li S, van Vugt MATM, Lans H, Bernards R, Svejstrup JQ, Ray Chaudhuri A, Wyrick JJ, Marteijn JA. Geijer ME, et al. Among authors: demmers jaa. Nat Cell Biol. 2021 Jul;23(7):809. doi: 10.1038/s41556-021-00720-y. Nat Cell Biol. 2021. PMID: 34163038 Free PMC article. No abstract available.
Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ.
Schellenbauer A, Guilly MN, Grall R, Le Bars R, Paget V, Kortulewski T, Sutcu H, Mathé C, Hullo M, Biard D, Leteurtre F, Barroca V, Corre Y, Irbah L, Rass E, Theze B, Bertrand P, Demmers JAA, Guirouilh-Barbat J, Lopez BS, Chevillard S, Delic J. Schellenbauer A, et al. Among authors: demmers jaa. Nucleic Acids Res. 2021 Nov 18;49(20):11728-11745. doi: 10.1093/nar/gkab980. Nucleic Acids Res. 2021. PMID: 34718776 Free PMC article.
100 results