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Page 1
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis.
Degiacomi G, Gianibbi B, Recchia D, Stelitano G, Truglio GI, Marra P, Stamilla A, Makarov V, Chiarelli LR, Manetti F, Pasca MR. Degiacomi G, et al. Among authors: stelitano g. ACS Omega. 2023 Jul 3;8(28):25209-25220. doi: 10.1021/acsomega.3c02311. eCollection 2023 Jul 18. ACS Omega. 2023. PMID: 37483251 Free PMC article.
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents.
Chiarelli LR, Mori M, Barlocco D, Beretta G, Gelain A, Pini E, Porcino M, Mori G, Stelitano G, Costantino L, Lapillo M, Bonanni D, Poli G, Tuccinardi T, Villa S, Meneghetti F. Chiarelli LR, et al. Among authors: stelitano g. Eur J Med Chem. 2018 Jul 15;155:754-763. doi: 10.1016/j.ejmech.2018.06.033. Epub 2018 Jun 18. Eur J Med Chem. 2018. PMID: 29940465 Free article.
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents.
Chiarelli LR, Mori M, Beretta G, Gelain A, Pini E, Sammartino JC, Stelitano G, Barlocco D, Costantino L, Lapillo M, Poli G, Caligiuri I, Rizzolio F, Bellinzoni M, Tuccinardi T, Villa S, Meneghetti F. Chiarelli LR, et al. Among authors: stelitano g. J Enzyme Inhib Med Chem. 2019 Dec;34(1):823-828. doi: 10.1080/14756366.2019.1589462. J Enzyme Inhib Med Chem. 2019. PMID: 30889995 Free PMC article.
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design.
Mori M, Stelitano G, Gelain A, Pini E, Chiarelli LR, Sammartino JC, Poli G, Tuccinardi T, Beretta G, Porta A, Bellinzoni M, Villa S, Meneghetti F. Mori M, et al. Among authors: stelitano g. J Med Chem. 2020 Jul 9;63(13):7066-7080. doi: 10.1021/acs.jmedchem.0c00373. Epub 2020 Jun 25. J Med Chem. 2020. PMID: 32530281 Free PMC article.
Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent.
Cazzaniga G, Mori M, Meneghetti F, Chiarelli LR, Stelitano G, Caligiuri I, Rizzolio F, Ciceri S, Poli G, Staver D, Ortore G, Tuccinardi T, Villa S. Cazzaniga G, et al. Among authors: stelitano g. Eur J Med Chem. 2022 Apr 15;234:114235. doi: 10.1016/j.ejmech.2022.114235. Epub 2022 Mar 5. Eur J Med Chem. 2022. PMID: 35286928
31 results