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Within-host rhinovirus evolution in upper and lower respiratory tract highlights capsid variability and mutation-independent compartmentalization.
Makhsous N, Goya S, Avendaño C, Rupp J, Kuypers J, Jerome KR, Boeckh M, Waghmare A, Greninger AL. Makhsous N, et al. bioRxiv [Preprint]. 2023 May 11:2023.05.11.540440. doi: 10.1101/2023.05.11.540440. bioRxiv. 2023. Update in: J Infect Dis. 2024 Feb 14;229(2):403-412. doi: 10.1093/infdis/jiad284 PMID: 37214809 Free PMC article. Updated. Preprint.
Gene editing and elimination of latent herpes simplex virus in vivo.
Aubert M, Strongin DE, Roychoudhury P, Loprieno MA, Haick AK, Klouser LM, Stensland L, Huang ML, Makhsous N, Tait A, De Silva Feelixge HS, Galetto R, Duchateau P, Greninger AL, Stone D, Jerome KR. Aubert M, et al. Among authors: makhsous n. Nat Commun. 2020 Aug 18;11(1):4148. doi: 10.1038/s41467-020-17936-5. Nat Commun. 2020. PMID: 32811834 Free PMC article.
Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Cox RM, et al. Among authors: makhsous n. Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661315 Free PMC article.
Trillions and Trillions: Herpes Simplex Virus-1 Hepatitis in an Immunocompetent Adult.
Ikuta K, Roychoudhury P, Xie H, Mcclurkan CL, Walkiewicz M, Makhsous N, Huang ML, Beru Y, Alam M, Shepherd A, Lamotte ED, Patel K, Morris A, Ҫoruh B, Yu L, Bhattacharya R, Cheng R, Walter RB, Limaye AP, Lockwood CM, Holland SM, Rakita RM, Koelle DM, Greninger AL. Ikuta K, et al. Among authors: makhsous n. Open Forum Infect Dis. 2019 Nov 5;6(11):ofz465. doi: 10.1093/ofid/ofz465. eCollection 2019 Nov. Open Forum Infect Dis. 2019. PMID: 31777756 Free PMC article.
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.
Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK. Toots M, et al. Among authors: makhsous n. Sci Transl Med. 2019 Oct 23;11(515):eaax5866. doi: 10.1126/scitranslmed.aax5866. Sci Transl Med. 2019. PMID: 31645453 Free PMC article.
20 results