Aladjem M - Search Results

1

ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.

Schultz CW, Zhang Y, Elmeskini R, Zimmermann A, Fu H, Murai Y, Wangsa D, Kumar S, Takahashi N, Atkinson D, Saha LK, Lee CF, Elenbaas B, Desai P, Sebastian R, Sharma AK, Abel M, Schroeder B, Krishnamurthy M, Kumar R, Roper N, Aladjem M, Zenke FT, Ohler ZW, Pommier Y, Thomas A. Schultz CW, et al. Among authors: aladjem m. EMBO Mol Med. 2023 Aug 7;15(8):e17313. doi: 10.15252/emmm.202217313. Epub 2023 Jul 25. EMBO Mol Med. 2023. PMID: 37491889 Free PMC article.

2

Dynamic alterations of replication timing in mammalian cells.

Lin CM, Fu H, Martinovsky M, Bouhassira E, Aladjem MI. Lin CM, et al. Among authors: aladjem mi. Curr Biol. 2003 Jun 17;13(12):1019-28. doi: 10.1016/s0960-9822(03)00382-8. Curr Biol. 2003. PMID: 12814547 Free article.

3

Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.

Aladjem MI, Pasa S, Parodi S, Weinstein JN, Pommier Y, Kohn KW. Aladjem MI, et al. Sci STKE. 2004 Feb 24;2004(222):pe8. doi: 10.1126/stke.2222004pe8. Sci STKE. 2004. PMID: 14997004 Review.

4

Molecular interaction maps of bioregulatory networks: a general rubric for systems biology.

Kohn KW, Aladjem MI, Weinstein JN, Pommier Y. Kohn KW, et al. Mol Biol Cell. 2006 Jan;17(1):1-13. doi: 10.1091/mbc.e05-09-0824. Epub 2005 Nov 2. Mol Biol Cell. 2006. PMID: 16267266 Free PMC article.

5

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bonner WM, Aladjem MI, Kohn KW, Pommier Y. Furuta T, et al. Among authors: aladjem mi. Oncogene. 2006 May 11;25(20):2839-49. doi: 10.1038/sj.onc.1209313. Oncogene. 2006. PMID: 16407843

6

Chk2 molecular interaction map and rationale for Chk2 inhibitors.

Pommier Y, Weinstein JN, Aladjem MI, Kohn KW. Pommier Y, et al. Clin Cancer Res. 2006 May 1;12(9):2657-61. doi: 10.1158/1078-0432.CCR-06-0743. Clin Cancer Res. 2006. PMID: 16675556

7

Depicting combinatorial complexity with the molecular interaction map notation.

Kohn KW, Aladjem MI, Kim S, Weinstein JN, Pommier Y. Kohn KW, et al. Mol Syst Biol. 2006;2:51. doi: 10.1038/msb4100088. Epub 2006 Oct 3. Mol Syst Biol. 2006. PMID: 17016517 Free PMC article. Review.

8

The cyclin-dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles.

Hong A, Narbonne-Reveau K, Riesgo-Escovar J, Fu H, Aladjem MI, Lilly MA. Hong A, et al. EMBO J. 2007 Apr 18;26(8):2071-82. doi: 10.1038/sj.emboj.7601648. Epub 2007 Mar 22. EMBO J. 2007. PMID: 17380129 Free PMC article.

9

The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses.

Seiler JA, Conti C, Syed A, Aladjem MI, Pommier Y. Seiler JA, et al. Mol Cell Biol. 2007 Aug;27(16):5806-18. doi: 10.1128/MCB.02278-06. Epub 2007 May 21. Mol Cell Biol. 2007. PMID: 17515603 Free PMC article.

10

Chromatin challenges during DNA replication: a systems representation.

Kohn KW, Aladjem MI, Weinstein JN, Pommier Y. Kohn KW, et al. Mol Biol Cell. 2008 Jan;19(1):1-7. doi: 10.1091/mbc.e07-06-0528. Epub 2007 Oct 24. Mol Biol Cell. 2008. PMID: 17959828 Free PMC article. Review.

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