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Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization.
Jahn D, Knapstein PR, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto MN, Beule D, Frosch KH, Baranowsky A, Tsitsilonis S, Keller J. Jahn D, et al. Among authors: jiang s. bioRxiv [Preprint]. 2023 Jul 16:2023.07.14.548550. doi: 10.1101/2023.07.14.548550. bioRxiv. 2023. Update in: Sci Transl Med. 2024 Apr 17;16(743):eadk9129. doi: 10.1126/scitranslmed.adk9129. PMID: 37502964 Free PMC article. Updated. Preprint.
Relevance of Notch Signaling for Bone Metabolism and Regeneration.
Ballhause TM, Jiang S, Baranowsky A, Brandt S, Mertens PR, Frosch KH, Yorgan T, Keller J. Ballhause TM, et al. Among authors: jiang s. Int J Mol Sci. 2021 Jan 29;22(3):1325. doi: 10.3390/ijms22031325. Int J Mol Sci. 2021. PMID: 33572704 Free PMC article. Review.
Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing.
Appelt J, Tsitsilonis S, Otto E, Jahn D, Köhli P, Baranowsky A, Jiang S, Fuchs M, Bucher CH, Duda GN, Frosch KH, Keller J. Appelt J, et al. Among authors: jiang s. Cells. 2021 Sep 3;10(9):2304. doi: 10.3390/cells10092304. Cells. 2021. PMID: 34571953 Free PMC article.
Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment.
Baranowsky A, Jahn D, Jiang S, Yorgan T, Ludewig P, Appelt J, Albrecht KK, Otto E, Knapstein P, Donat A, Winneberger J, Rosenthal L, Köhli P, Erdmann C, Fuchs M, Frosch KH, Tsitsilonis S, Amling M, Schinke T, Keller J. Baranowsky A, et al. Among authors: jiang s. Bone Res. 2022 Jan 27;10(1):9. doi: 10.1038/s41413-021-00172-y. Bone Res. 2022. PMID: 35087025 Free PMC article.
Systemic calcitonin gene-related peptide receptor antagonism decreases survival in a porcine model of polymicrobial sepsis: blinded randomised controlled trial.
Messerer DAC, Datzmann T, Baranowsky A, Peschel L, Hoffmann A, Gröger M, Amling M, Wepler M, Nussbaum BL, Jiang S, Knapstein P, Donat A, Calzia E, Radermacher P, Keller J. Messerer DAC, et al. Among authors: jiang s. Br J Anaesth. 2022 May;128(5):864-873. doi: 10.1016/j.bja.2021.11.042. Epub 2022 Feb 4. Br J Anaesth. 2022. PMID: 35131096 Free article. Clinical Trial.
Inactivation of the gene encoding procalcitonin prevents antibody-mediated arthritis.
Maleitzke T, Dietrich T, Hildebrandt A, Weber J, Appelt J, Jahn D, Otto E, Zocholl D, Jiang S, Baranowsky A, Duda GN, Tsitsilonis S, Keller J. Maleitzke T, et al. Among authors: jiang s. Inflamm Res. 2023 May;72(5):1069-1081. doi: 10.1007/s00011-023-01719-x. Epub 2023 Apr 11. Inflamm Res. 2023. PMID: 37039837
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