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FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration.
Kodavati M, Wang H, Guo W, Mitra J, Hegde PM, Provasek V, Maloji Rao VH, Vedula I, Zhang A, Mitra S, Tomkinson AE, Hamilton DJ, Bosch LVD, Hegde ML. Kodavati M, et al. Among authors: guo w. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-3152718. doi: 10.21203/rs.3.rs-3152718/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Mar 9;15(1):2156. doi: 10.1038/s41467-024-45978-6 PMID: 37502965 Free PMC article. Updated. Preprint.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
lncRNA Sequencing Reveals Neurodegeneration-associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists In Motor Neurons.
Provasek VE, Kodavati M, Guo W, Wang H, Boldogh I, Van Den Bosch L, Britz G, Hegde M. Provasek VE, et al. Among authors: guo w. Res Sq [Preprint]. 2023 Jun 27:rs.3.rs-3112246. doi: 10.21203/rs.3.rs-3112246/v1. Res Sq. 2023. Update in: Cells. 2023 Oct 16;12(20):2461. doi: 10.3390/cells12202461 PMID: 37461717 Free PMC article. Updated. Preprint.
Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F, Kalmbach N, Naujock M, Staege S, Eggenschwiler R, Abo-Rady M, Japtok J, Guo W, Hensel N, Reinhardt P, Boeckers TM, Cantz T, Sterneckert J, Van Den Bosch L, Hermann A, Petri S, Wegner F. Bursch F, et al. Among authors: guo w. Hum Mol Genet. 2019 Sep 1;28(17):2835-2850. doi: 10.1093/hmg/ddz107. Hum Mol Genet. 2019. PMID: 31108504
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