Sakamuru S - Search Results

1

High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.

Lynch C, Sakamuru S, Ooka M, Huang R, Klumpp-Thomas C, Shinn P, Gerhold D, Rossoshek A, Michael S, Casey W, Santillo MF, Fitzpatrick S, Thomas RS, Simeonov A, Xia M. Lynch C, et al. Among authors: sakamuru s. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:191-209. doi: 10.1146/annurev-pharmtox-112122-104310. Epub 2023 Jul 28. Annu Rev Pharmacol Toxicol. 2024. PMID: 37506331 Free PMC article. Review.

2

Identification of small molecule compounds that inhibit the HIF-1 signaling pathway.

Xia M, Bi K, Huang R, Cho MH, Sakamuru S, Miller SC, Li H, Sun Y, Printen J, Austin CP, Inglese J. Xia M, et al. Among authors: sakamuru s. Mol Cancer. 2009 Dec 9;8:117. doi: 10.1186/1476-4598-8-117. Mol Cancer. 2009. PMID: 20003191 Free PMC article.

3

Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action.

Miller SC, Huang R, Sakamuru S, Shukla SJ, Attene-Ramos MS, Shinn P, Van Leer D, Leister W, Austin CP, Xia M. Miller SC, et al. Among authors: sakamuru s. Biochem Pharmacol. 2010 May 1;79(9):1272-80. doi: 10.1016/j.bcp.2009.12.021. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067776 Free PMC article.

4

Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity.

Judson RS, Martin MT, Reif DM, Houck KA, Knudsen TB, Rotroff DM, Xia M, Sakamuru S, Huang R, Shinn P, Austin CP, Kavlock RJ, Dix DJ. Judson RS, et al. Among authors: sakamuru s. Environ Sci Technol. 2010 Aug 1;44(15):5979-85. doi: 10.1021/es102150z. Environ Sci Technol. 2010. PMID: 20602530 Free PMC article.

5

Identification of clinically used drugs that activate pregnane X receptors.

Shukla SJ, Sakamuru S, Huang R, Moeller TA, Shinn P, Vanleer D, Auld DS, Austin CP, Xia M. Shukla SJ, et al. Among authors: sakamuru s. Drug Metab Dispos. 2011 Jan;39(1):151-9. doi: 10.1124/dmd.110.035105. Epub 2010 Oct 21. Drug Metab Dispos. 2011. PMID: 20966043 Free PMC article.

6

Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

Huang R, Xia M, Cho MH, Sakamuru S, Shinn P, Houck KA, Dix DJ, Judson RS, Witt KL, Kavlock RJ, Tice RR, Austin CP. Huang R, et al. Among authors: sakamuru s. Environ Health Perspect. 2011 Aug;119(8):1142-8. doi: 10.1289/ehp.1002952. Epub 2011 May 4. Environ Health Perspect. 2011. PMID: 21543282 Free PMC article.

7

Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors.

Huang W, Huang R, Attene-Ramos MS, Sakamuru S, Englund EE, Inglese J, Austin CP, Xia M. Huang W, et al. Among authors: sakamuru s. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5239-43. doi: 10.1016/j.bmcl.2011.07.043. Epub 2011 Jul 21. Bioorg Med Chem Lett. 2011. PMID: 21831635 Free PMC article.

8

High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.

Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K. Fox JT, et al. Among authors: sakamuru s. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5423-8. doi: 10.1073/pnas.1114278109. Epub 2012 Mar 19. Proc Natl Acad Sci U S A. 2012. PMID: 22431602 Free PMC article.

9

Application of a homogenous membrane potential assay to assess mitochondrial function.

Sakamuru S, Li X, Attene-Ramos MS, Huang R, Lu J, Shou L, Shen M, Tice RR, Austin CP, Xia M. Sakamuru S, et al. Physiol Genomics. 2012 May 1;44(9):495-503. doi: 10.1152/physiolgenomics.00161.2011. Epub 2012 Mar 20. Physiol Genomics. 2012. PMID: 22433785 Free PMC article.

10

Identification of repurposed small molecule drugs for chordoma therapy.

Xia M, Huang R, Sakamuru S, Alcorta D, Cho MH, Lee DH, Park DM, Kelley MJ, Sommer J, Austin CP. Xia M, et al. Among authors: sakamuru s. Cancer Biol Ther. 2013 Jul;14(7):638-47. doi: 10.4161/cbt.24596. Epub 2013 May 10. Cancer Biol Ther. 2013. PMID: 23792643 Free PMC article.

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