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Mechanisms and clinical relevance of the bidirectional relationship of viral infections with metabolic diseases.
Perakakis N, Harb H, Hale BG, Varga Z, Steenblock C, Kanczkowski W, Alexaki VI, Ludwig B, Mirtschink P, Solimena M, Toepfner N, Zeissig S, Gado M, Abela IA, Beuschlein F, Spinas GA, Cavelti-Weder C, Gerber PA, Huber M, Trkola A, Puhan MA, Wong WW, Linkermann A, Mohan V, Lehnert H, Nawroth P, Chavakis T, Mingrone G, Wolfrum C, Zinkernagel AS, Bornstein SR. Perakakis N, et al. Among authors: hale bg. Lancet Diabetes Endocrinol. 2023 Sep;11(9):675-693. doi: 10.1016/S2213-8587(23)00154-7. Epub 2023 Jul 28. Lancet Diabetes Endocrinol. 2023. PMID: 37524103 Review.
Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies.
Fernbach S, Mair NK, Abela IA, Groen K, Kuratli R, Lork M, Thorball CW, Bernasconi E, Filippidis P, Leuzinger K, Notter J, Rauch A, Hirsch HH, Huber M, Günthard HF, Fellay J, Kouyos RD, Hale BG; Swiss HIV Cohort Study. Fernbach S, et al. Among authors: hale bg. J Exp Med. 2024 Sep 2;221(9):e20240365. doi: 10.1084/jem.20240365. Epub 2024 Jul 17. J Exp Med. 2024. PMID: 39017930 Free PMC article.
Absence of Type I Interferon Autoantibodies or Significant Interferon Signature Alterations in Adults With Post-COVID-19 Syndrome.
Achleitner M, Mair NK, Dänhardt J, Kardashi R, Puhan MA, Abela IA, Toepfner N, de With K, Kanczkowski W, Jarzebska N, Rodionov RN, Wolf C, Lee-Kirsch MA, Steenblock C, Hale BG, Bornstein SR. Achleitner M, et al. Among authors: hale bg. Open Forum Infect Dis. 2023 Dec 19;11(1):ofad641. doi: 10.1093/ofid/ofad641. eCollection 2024 Jan. Open Forum Infect Dis. 2023. PMID: 38179103 Free PMC article.
vPIF-1 is an insulin-like antiferroptotic viral peptide.
Belavgeni A, Maremonti F, Tonnus W, Stadtmüller M, Gavali S, Mallais M, Flade K, Brucker A, Becker JN, Beer K, Tmava M, Stumpf J, Gembardt F, Hugo C, Giacca M, Hale BG, Perakakis N, Sha W, Pratt DA, Schally AV, Bornstein SR, Linkermann A. Belavgeni A, et al. Among authors: hale bg. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2300320120. doi: 10.1073/pnas.2300320120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186845 Free PMC article.
SARS-CoV-2 takes the bait: Exosomes as endogenous decoys.
Fernbach S, Hale BG. Fernbach S, et al. Among authors: hale bg. PLoS Biol. 2022 Sep 14;20(9):e3001787. doi: 10.1371/journal.pbio.3001787. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36103486 Free PMC article.
59 results