Lau AY - Search Results

1

Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism.

Britton BM, Yovanno RA, Costa SF, McCausland J, Lau AY, Xiao J, Hensel Z. Britton BM, et al. Among authors: lau ay. Nat Commun. 2023 Jul 31;14(1):4585. doi: 10.1038/s41467-023-39921-4. Nat Commun. 2023. PMID: 37524712 Free PMC article.

2

D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2.

Chin AC, Yovanno RA, Wied TJ, Gershman A, Lau AY. Chin AC, et al. Among authors: lau ay. Structure. 2020 Oct 6;28(10):1168-1178.e2. doi: 10.1016/j.str.2020.07.005. Epub 2020 Jul 30. Structure. 2020. PMID: 32735769 Free PMC article.

3

Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.

Matyszewski M, Zheng W, Lueck J, Mazanek Z, Mohideen N, Lau AY, Egelman EH, Sohn J. Matyszewski M, et al. Among authors: lau ay. Nat Commun. 2021 May 12;12(1):2735. doi: 10.1038/s41467-021-23045-8. Nat Commun. 2021. PMID: 33980849 Free PMC article.

4

Finding Druggable Sites in Proteins Using TACTICS.

Evans DJ, Yovanno RA, Rahman S, Cao DW, Beckett MQ, Patel MH, Bandak AF, Lau AY. Evans DJ, et al. Among authors: lau ay. J Chem Inf Model. 2021 Jun 28;61(6):2897-2910. doi: 10.1021/acs.jcim.1c00204. Epub 2021 Jun 7. J Chem Inf Model. 2021. PMID: 34096704 Free PMC article.

5

Development and characterization of functional antibodies targeting NMDA receptors.

Tajima N, Simorowski N, Yovanno RA, Regan MC, Michalski K, Gómez R, Lau AY, Furukawa H. Tajima N, et al. Among authors: lau ay. Nat Commun. 2022 Feb 17;13(1):923. doi: 10.1038/s41467-022-28559-3. Nat Commun. 2022. PMID: 35177668 Free PMC article.

6

Excitatory and inhibitory D-serine binding to the NMDA receptor.

Yovanno RA, Chou TH, Brantley SJ, Furukawa H, Lau AY. Yovanno RA, et al. Among authors: lau ay. Elife. 2022 Oct 27;11:e77645. doi: 10.7554/eLife.77645. Elife. 2022. PMID: 36301074 Free PMC article.

7

Phosphorylation at Ser65 modulates ubiquitin conformational dynamics.

Yovanno RA, Yu A, Wied TJ, Lau AY. Yovanno RA, et al. Among authors: lau ay. Structure. 2023 Jul 6;31(7):884-890.e2. doi: 10.1016/j.str.2023.05.006. Epub 2023 Jun 1. Structure. 2023. PMID: 37267945 Free PMC article.

8

A conformational intermediate in glutamate receptor activation.

Lau AY, Salazar H, Blachowicz L, Ghisi V, Plested AJ, Roux B. Lau AY, et al. Neuron. 2013 Aug 7;79(3):492-503. doi: 10.1016/j.neuron.2013.06.003. Neuron. 2013. PMID: 23931998 Free PMC article.

9

Allosteric competition and inhibition in AMPA receptors.

Hale WD, Montaño Romero A, Gonzalez CU, Jayaraman V, Lau AY, Huganir RL, Twomey EC. Hale WD, et al. Among authors: lau ay. Nat Struct Mol Biol. 2024 Jun 4. doi: 10.1038/s41594-024-01328-0. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38834914

10

Sodium/Iodide Symporter Metastable Intermediates Provide Insights into Conformational Transition between Principal Thermodynamic States.

Chakrabarti M, Amzel LM, Lau AY. Chakrabarti M, et al. Among authors: lau ay. J Phys Chem B. 2023 Feb 23;127(7):1540-1551. doi: 10.1021/acs.jpcb.2c07604. Epub 2023 Feb 9. J Phys Chem B. 2023. PMID: 36758032

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