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Page 1
Genetic insights into resting heart rate and its role in cardiovascular disease.
van de Vegte YJ, Eppinga RN, van der Ende MY, Hagemeijer YP, Mahendran Y, Salfati E, Smith AV, Tan VY, Arking DE, Ntalla I, Appel EV, Schurmann C, Brody JA, Rueedi R, Polasek O, Sveinbjornsson G, Lecoeur C, Ladenvall C, Zhao JH, Isaacs A, Wang L, Luan J, Hwang SJ, Mononen N, Auro K, Jackson AU, Bielak LF, Zeng L, Shah N, Nethander M, Campbell A, Rankinen T, Pechlivanis S, Qi L, Zhao W, Rizzi F, Tanaka T, Robino A, Cocca M, Lange L, Müller-Nurasyid M, Roselli C, Zhang W, Kleber ME, Guo X, Lin HJ, Pavani F, Galesloot TE, Noordam R, Milaneschi Y, Schraut KE, den Hoed M, Degenhardt F, Trompet S, van den Berg ME, Pistis G, Tham YC, Weiss S, Sim XS, Li HL, van der Most PJ, Nolte IM, Lyytikäinen LP, Said MA, Witte DR, Iribarren C, Launer L, Ring SM, de Vries PS, Sever P, Linneberg A, Bottinger EP, Padmanabhan S, Psaty BM, Sotoodehnia N, Kolcic I; DCCT/EDIC Research Group; Arnar DO, Gudbjartsson DF, Holm H, Balkau B, Silva CT, Newton-Cheh CH, Nikus K, Salo P, Mohlke KL, Peyser PA, Schunkert H, Lorentzon M, Lahti J, Rao DC, Cornelis MC, Faul JD, Smith JA, Stolarz-Skrzypek K, Bandinelli S, Concas MP, Sinagra G, Meitinger T, Waldenberger M, Sinner MF, Strauch K, Delgado GE, Taylor KD,… See abstract for full author list ➔ van de Vegte YJ, et al. Among authors: tan vy. Nat Commun. 2023 Aug 2;14(1):4646. doi: 10.1038/s41467-023-39521-2. Nat Commun. 2023. PMID: 37532724 Free PMC article.
The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.
Kalaoja M, Corbin LJ, Tan VY, Ahola-Olli AV, Havulinna AS, Santalahti K, Pitkänen N, Lehtimäki T, Lyytikäinen LP, Raitoharju E, Seppälä I, Kähönen M, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salomaa V, Salmi M, Raitakari OT, Kettunen J, Timpson NJ. Kalaoja M, et al. Among authors: tan vy. Obesity (Silver Spring). 2021 Feb;29(2):428-437. doi: 10.1002/oby.23060. Obesity (Silver Spring). 2021. PMID: 33491305 Free PMC article.
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.
Corbin LJ, Tan VY, Hughes DA, Wade KH, Paul DS, Tansey KE, Butcher F, Dudbridge F, Howson JM, Jallow MW, John C, Kingston N, Lindgren CM, O'Donavan M, O'Rahilly S, Owen MJ, Palmer CNA, Pearson ER, Scott RA, van Heel DA, Whittaker J, Frayling T, Tobin MD, Wain LV, Smith GD, Evans DM, Karpe F, McCarthy MI, Danesh J, Franks PW, Timpson NJ. Corbin LJ, et al. Among authors: tan vy. Nat Commun. 2018 Feb 19;9(1):711. doi: 10.1038/s41467-018-03109-y. Nat Commun. 2018. PMID: 29459775 Free PMC article. Review.
Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study.
Tan VY, Bull CJ, Biernacka KM, Teumer A, Richardson TG, Sanderson E, Corbin LJ, Dudding T, Qi Q, Kaplan RC, Rotter JI, Friedrich N, Völker U, Mayerle J, Perks CM, Holly JMP, Timpson NJ. Tan VY, et al. Cancer Epidemiol Biomarkers Prev. 2021 Dec;30(12):2207-2216. doi: 10.1158/1055-9965.EPI-21-0315. Epub 2021 Sep 28. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 34583967 Free PMC article.
Reassessing the Association between Circulating Vitamin D and IGFBP-3: Observational and Mendelian Randomization Estimates from Independent Sources.
Tan VY, Biernacka KM, Dudding T, Bonilla C, Gilbert R, Kaplan RC, Qibin Q, Teumer A, Martin RM, Perks CM, Timpson NJ, Holly JMP; PRACTICAL consortium. Tan VY, et al. Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1462-1471. doi: 10.1158/1055-9965.EPI-18-0113. Epub 2018 Aug 2. Cancer Epidemiol Biomarkers Prev. 2018. PMID: 30072546 Free PMC article.
The MR-Base platform supports systematic causal inference across the human phenome.
Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, Laurin C, Burgess S, Bowden J, Langdon R, Tan VY, Yarmolinsky J, Shihab HA, Timpson NJ, Evans DM, Relton C, Martin RM, Davey Smith G, Gaunt TR, Haycock PC. Hemani G, et al. Among authors: tan vy. Elife. 2018 May 30;7:e34408. doi: 10.7554/eLife.34408. Elife. 2018. PMID: 29846171 Free PMC article.
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
Guida F, Tan VY, Corbin LJ, Smith-Byrne K, Alcala K, Langenberg C, Stewart ID, Butterworth AS, Surendran P, Achaintre D, Adamski J, Amiano P, Bergmann MM, Bull CJ, Dahm CC, Gicquiau A, Giles GG, Gunter MJ, Haller T, Langhammer A, Larose TL, Ljungberg B, Metspalu A, Milne RL, Muller DC, Nøst TH, Pettersen Sørgjerd E, Prehn C, Riboli E, Rinaldi S, Rothwell JA, Scalbert A, Schmidt JA, Severi G, Sieri S, Vermeulen R, Vincent EE, Waldenberger M, Timpson NJ, Johansson M. Guida F, et al. Among authors: tan vy. PLoS Med. 2021 Sep 20;18(9):e1003786. doi: 10.1371/journal.pmed.1003786. eCollection 2021 Sep. PLoS Med. 2021. PMID: 34543281 Free PMC article.
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Gill D, Arvanitis M, Carter P, Hernández Cordero AI, Jo B, Karhunen V, Larsson SC, Li X, Lockhart SM, Mason A, Pashos E, Saha A, Tan VY, Zuber V, Bossé Y, Fahle S, Hao K, Jiang T, Joubert P, Lunt AC, Ouwehand WH, Roberts DJ, Timens W, van den Berge M, Watkins NA, Battle A, Butterworth AS, Danesh J, Di Angelantonio E, Engelhardt BE, Peters JE, Sin DD, Burgess S. Gill D, et al. Among authors: tan vy. R Soc Open Sci. 2020 Nov 18;7(11):200958. doi: 10.1098/rsos.200958. eCollection 2020 Nov. R Soc Open Sci. 2020. PMID: 33391794 Free PMC article.
45 results