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Page 1
Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis.
Brothwell MJ, Cao 曹国燊 G, Maschek JA, Poss AM, Peterlin AD, Wang 汪立平 L, Baker TB, Shahtout JL, Siripoksup P, Pearce QJ, Johnson JM, Finger FM, Prola A, Pellizzari SA, Hale GL, Manuel AM, Watanabe 渡邉真也 S, Miranda ER, Affolter KE, Tippetts TS, Nikolova LS, Choi 崔蘭煕 RH, Decker ST, Patil M, Catrow JL, Holland WL, Nowinski SM, Lark DS, Fisher-Wellman KH, Mimche PN, Evason KJ, Cox JE, Summers SA, Gerhart-Hines Z, Funai 船井勝彦 K. Brothwell MJ, et al. Among authors: maschek ja. bioRxiv [Preprint]. 2024 Oct 10:2024.10.10.617517. doi: 10.1101/2024.10.10.617517. bioRxiv. 2024. PMID: 39416056 Free PMC article. Preprint.
HAF prevents hepatocyte apoptosis and progression to MASH and HCC through transcriptional regulation of the NF-κB pathway.
Acuña-Pilarte K, Reichert EC, Green YS, Halberg LM, Golkowski M, Maguire KM, Mimche PN, Kamdem SD, Hu PA, Wright J, Ducker GS, Voth WP, O'Connell RM, McFarland SA, Egal ESA, Chaix A, Summers SA, Reelitz JW, Maschek JA, Cox JE, Evason KJ, Koh MY. Acuña-Pilarte K, et al. Among authors: maschek ja. Hepatology. 2024 Sep 10. doi: 10.1097/HEP.0000000000001070. Online ahead of print. Hepatology. 2024. PMID: 39255518
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Brothwell MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. Among authors: maschek ja. J Clin Invest. 2024 Apr 23;134(11):e167371. doi: 10.1172/JCI167371. J Clin Invest. 2024. PMID: 38652544 Free PMC article.
Adiponectin overexpression improves metabolic abnormalities caused by acid ceramidase deficiency but does not prolong lifespan in a mouse model of Farber Disease.
Norris MK, Tippetts TS, Wilkerson JL, Nicholson RJ, Maschek JA, Levade T, Medin JA, Summers SA, Holland WL. Norris MK, et al. Among authors: maschek ja. Mol Genet Metab Rep. 2024 Apr 3;39:101077. doi: 10.1016/j.ymgmr.2024.101077. eCollection 2024 Jun. Mol Genet Metab Rep. 2024. PMID: 38595987 Free PMC article.
HAF Prevents Hepatocyte Apoptosis and Hepatocellular Carcinoma through Transcriptional Regulation of the NF-κB pathway.
Pilarte KA, Reichert EC, Green YS, Halberg LM, McFarland SA, Mimche PN, Golkowski M, Kamdem SD, Maguire KM, Summers SA, Maschek JA, Reelitz JW, Cox JE, Evason KJ, Koh MY. Pilarte KA, et al. Among authors: maschek ja. bioRxiv [Preprint]. 2024 Jan 11:2024.01.09.574894. doi: 10.1101/2024.01.09.574894. bioRxiv. 2024. Update in: Hepatology. 2024 Sep 10. doi: 10.1097/HEP.0000000000001070 PMID: 38260413 Free PMC article. Updated. Preprint.
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