Zhao YL - Search Results

1

Facilitated Drug Repurposing with Artemisinin-Derived PROTACs: Unveiling PCLAF as a Therapeutic Target.

Li Y, Zeng ZW, Chen D, Gu ZC, Yan WL, Yue LY, Zhu RG, Zhao YL, Chen L, Zhao QJ, He B. Li Y, et al. Among authors: zhao qj, zhao yl. J Med Chem. 2023 Aug 24;66(16):11335-11350. doi: 10.1021/acs.jmedchem.3c00824. Epub 2023 Aug 8. J Med Chem. 2023. PMID: 37552639

2

Zinc-dependent Deacetylase (HDAC) Inhibitors with Different Zinc Binding Groups.

Li Y, Wang F, Chen X, Wang J, Zhao Y, Li Y, He B. Li Y, et al. Curr Top Med Chem. 2019;19(3):223-241. doi: 10.2174/1568026619666190122144949. Curr Top Med Chem. 2019. PMID: 30674261 Review.

3

Organocatalytic Asymmetric α-Sulfenylation of 2-Substituted Indolin-3-ones: A Strategy for the Synthesis of Chiral 2,2-Disubstituted Indole-3-ones with S- and N-Containing Heteroquaternary Carbon Stereocenter.

Zhao YL, Fei XH, Tang YQ, Xu PF, Yang FF, He B, Fu XZ, Yang YY, Zhou M, Mao YH, Dong YX, Li C. Zhao YL, et al. J Org Chem. 2019 Jun 21;84(12):8168-8176. doi: 10.1021/acs.joc.9b01142. Epub 2019 Jun 13. J Org Chem. 2019. PMID: 31192597

4

Synthesis, pharmacological evaluation, and mechanistic study of adefovir mixed phosphonate derivatives bearing cholic acid and l-amino acid moieties for the treatment of HBV.

Li T, Li J, Yang Y, Han Y, Wu D, Xiao T, Wang Y, Liu T, Zhao Y, Li Y, Dai Z, Fu X. Li T, et al. Bioorg Med Chem. 2019 Aug 15;27(16):3707-3721. doi: 10.1016/j.bmc.2019.07.012. Epub 2019 Jul 8. Bioorg Med Chem. 2019. PMID: 31301948

5

N ^ɛ -acetyl lysine derivatives with zinc binding groups as novel HDAC inhibitors.

Wang F, Wang C, Wang J, Zou Y, Chen X, Liu T, Li Y, Zhao Y, Li Y, He B. Wang F, et al. R Soc Open Sci. 2019 Jun 5;6(6):190338. doi: 10.1098/rsos.190338. eCollection 2019 Jun. R Soc Open Sci. 2019. PMID: 31312496 Free PMC article.

6

Unexpected small molecules as novel SIRT2 suicide inhibitors.

Chen X, Zou Y, Wang J, Cao Z, Liu J, Li Y, Zhao Y, He B. Chen X, et al. Bioorg Med Chem. 2020 Mar 15;28(6):115353. doi: 10.1016/j.bmc.2020.115353. Epub 2020 Feb 5. Bioorg Med Chem. 2020. PMID: 32061485

7

A Series of Novel HDAC Inhibitors with Anthraquinone as a Cap Group.

Zou Y, Cao Z, Wang J, Chen X, Chen YQ, Li Y, Liu J, Zhao Y, Wang A, He B. Zou Y, et al. Chem Pharm Bull (Tokyo). 2020;68(7):613-617. doi: 10.1248/cpb.c20-00206. Chem Pharm Bull (Tokyo). 2020. PMID: 32611998 Free article.

8

Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.

Wang S, Zhang RH, Zhang H, Wang YC, Yang D, Zhao YL, Yan GY, Xu GB, Guan HY, Zhou YH, Cui DB, Liu T, Li YJ, Liao SG, Zhou M. Wang S, et al. Among authors: zhao yl. Eur J Med Chem. 2021 Oct 15;222:113573. doi: 10.1016/j.ejmech.2021.113573. Epub 2021 May 29. Eur J Med Chem. 2021. PMID: 34091209

9

Discovery of β-Carboline Derivatives as a Highly Potent Cardioprotectant against Myocardial Ischemia-Reperfusion Injury.

Zhang H, Zhang RH, Liao XM, Yang D, Wang YC, Zhao YL, Xu GB, Liu CH, Li YJ, Liao SG, Zhou M. Zhang H, et al. Among authors: zhao yl. J Med Chem. 2021 Jul 8;64(13):9166-9181. doi: 10.1021/acs.jmedchem.1c00384. Epub 2021 Jun 16. J Med Chem. 2021. PMID: 34132541

10

Cysteine derivatives as acetyl lysine mimics to inhibit zinc-dependent histone deacetylases for treating cancer.

Wang J, Cao Z, Wang F, Wang P, An J, Fu X, Liu T, Li Y, Li Y, Zhao Y, Lin H, He B. Wang J, et al. Eur J Med Chem. 2021 Dec 5;225:113799. doi: 10.1016/j.ejmech.2021.113799. Epub 2021 Aug 27. Eur J Med Chem. 2021. PMID: 34500130

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