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Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice.
Meade RK, Long JE, Jinich A, Rhee KY, Ashbrook DG, Williams RW, Sassetti CM, Smith CM. Meade RK, et al. Among authors: williams rw. bioRxiv [Preprint]. 2023 Mar 6:2023.03.05.528534. doi: 10.1101/2023.03.05.528534. bioRxiv. 2023. Update in: G3 (Bethesda). 2023 Aug 30;13(9):jkad147. doi: 10.1093/g3journal/jkad147 PMID: 36945430 Free PMC article. Updated. Preprint.
Merged magnetic resonance and light sheet microscopy of the whole mouse brain.
Johnson GA, Tian Y, Ashbrook DG, Cofer GP, Cook JJ, Gee JC, Hall A, Hornburg K, Kaczorowski CC, Qi Y, Yeh FC, Wang N, White LE, Williams RW. Johnson GA, et al. Among authors: williams rw. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2218617120. doi: 10.1073/pnas.2218617120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068254 Free PMC article.
Building pangenome graphs.
Garrison E, Guarracino A, Heumos S, Villani F, Bao Z, Tattini L, Hagmann J, Vorbrugg S, Marco-Sola S, Kubica C, Ashbrook DG, Thorell K, Rusholme-Pilcher RL, Liti G, Rudbeck E, Golicz AA, Nahnsen S, Yang Z, Mwaniki MN, Nobrega FL, Wu Y, Chen H, de Ligt J, Sudmant PH, Huang S, Weigel D, Soranzo N, Colonna V, Williams RW, Prins P. Garrison E, et al. Among authors: williams rw. Nat Methods. 2024 Nov;21(11):2008-2012. doi: 10.1038/s41592-024-02430-3. Epub 2024 Oct 21. Nat Methods. 2024. PMID: 39433878
IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.
Pan L, Cho KS, Wei X, Xu F, Lennikov A, Hu G, Tang J, Guo S, Chen J, Kriukov E, Kyle R, Elzaridi F, Jiang S, Dromel PA, Young M, Baranov P, Do CW, Williams RW, Chen J, Lu L, Chen DF. Pan L, et al. Among authors: williams rw. Cell Rep. 2023 Aug 29;42(8):112889. doi: 10.1016/j.celrep.2023.112889. Epub 2023 Jul 31. Cell Rep. 2023. PMID: 37527036 Free PMC article.
620 results