King-Ahmad A - Search Results

1

Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.

Huh Y, Plotka A, Wei H, Kaplan J, Raha N, Towner J, Purohit VS, Dowty ME, Wolk R, Vourvahis M, King-Ahmad A, Mathialagan S, West MA, Lazzaro S, Ryu S, Rodrigues AD. Huh Y, et al. Among authors: king ahmad a. Pharm Res. 2023 Nov;40(11):2639-2651. doi: 10.1007/s11095-023-03564-3. Epub 2023 Aug 10. Pharm Res. 2023. PMID: 37561322 Free PMC article.

2

A highly selective and sensitive LC-MS/HRMS assay for quantifying coproporphyrins as organic anion-transporting peptide biomarkers.

Ramanathan R, King-Ahmad AJ, Holliman CL, Rodrigues AD. Ramanathan R, et al. Bioanalysis. 2017 Nov;9(22):1787-1806. doi: 10.4155/bio-2017-0181. Epub 2017 Oct 5. Bioanalysis. 2017. PMID: 28978230

3

A fully automated and validated human plasma LC-MS/MS assay for endogenous OATP biomarkers coproporphyrin-I and coproporphyrin-III.

King-Ahmad A, Clemens S, Ramanathan R, Zhang Y, Raha N, Zhang Y, Holliman C, Rodrigues AD, Li F. King-Ahmad A, et al. Bioanalysis. 2018 May 1;10(9):691-701. doi: 10.4155/bio-2017-0270. Epub 2018 May 11. Bioanalysis. 2018. PMID: 29747517

4

Effect of a Ketohexokinase Inhibitor (PF-06835919) on In Vivo OATP1B Activity: Integrative Risk Assessment Using Endogenous Biomarker and a Probe Drug.

Tess DA, Kimoto E, King-Ahmad A, Vourvahis M, Rodrigues AD, Bergman A, Qui R, Somayaji V, Weng Y, Fonseca KR, Litchfield J, Varma MVS. Tess DA, et al. Among authors: king ahmad a. Clin Pharmacol Ther. 2022 Sep;112(3):605-614. doi: 10.1002/cpt.2593. Epub 2022 May 9. Clin Pharmacol Ther. 2022. PMID: 35355249

5

The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans.

Bauman JN, Doran AC, King-Ahmad A, Sharma R, Walker GS, Lin J, Lin TH, Telliez JB, Tripathy S, Goosen TC, Banfield C, Malhotra BK, Dowty ME. Bauman JN, et al. Among authors: king ahmad a. Drug Metab Dispos. 2022 Aug;50(8):1106-1118. doi: 10.1124/dmd.122.000829. Epub 2022 Jun 14. Drug Metab Dispos. 2022. PMID: 35701182

6

Characterization of Bile Acid Sulfate Conjugates as Substrates of Human Organic Anion Transporting Polypeptides.

Orozco CC, Neuvonen M, Bi YA, Cerny MA, Mathialagan S, Tylaska L, Rago B, Costales C, King-Ahmad A, Niemi M, Rodrigues AD. Orozco CC, et al. Among authors: king ahmad a. Mol Pharm. 2023 Jun 5;20(6):3020-3032. doi: 10.1021/acs.molpharmaceut.3c00040. Epub 2023 May 3. Mol Pharm. 2023. PMID: 37134201

7

Dose-Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs.

Mori D, Kimoto E, Rago B, Kondo Y, King-Ahmad A, Ramanathan R, Wood LS, Johnson JG, Le VH, Vourvahis M, David Rodrigues A, Muto C, Furihata K, Sugiyama Y, Kusuhara H. Mori D, et al. Among authors: king ahmad a. Clin Pharmacol Ther. 2020 Apr;107(4):1004-1013. doi: 10.1002/cpt.1695. Epub 2020 Jan 1. Clin Pharmacol Ther. 2020. PMID: 31628668 Free PMC article. Clinical Trial.

8

In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey.

Trapa PE, Beaumont K, Atkinson K, Eng H, King-Ahmad A, Scott DO, Maurer TS, Di L. Trapa PE, et al. J Pharm Sci. 2017 Mar;106(3):898-905. doi: 10.1016/j.xphs.2016.12.001. Epub 2016 Dec 18. J Pharm Sci. 2017. PMID: 27998705

9

An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis.

Hollingshead BD, Tomlinson L, Finley J, Doshna C, Ritenour C, Barricklow J, Oppenheimer SR, O'Neil SP, Moore JL, Patterson NH, Nicholson SP, Norris JL, Caprioli RM, Beaumont K, King-Ahmad AJ, Vispute S, Cook JC, Radi Z, Schuler M. Hollingshead BD, et al. Among authors: king ahmad aj. Regul Toxicol Pharmacol. 2021 Jul;123:104934. doi: 10.1016/j.yrtph.2021.104934. Epub 2021 Apr 16. Regul Toxicol Pharmacol. 2021. PMID: 33872740

10

A sensitive method for the quantitation of the peptide-based glucagon-like peptide-1 receptor agonist liraglutide in plasma using microfluidics chromatography tandem MS.

King-Ahmad AJ, Kalgutkar AS, Niosi M, Eng H, Holliman C. King-Ahmad AJ, et al. Bioanalysis. 2018 Mar 1;10(5):357-368. doi: 10.4155/bio-2017-0239. Epub 2018 Mar 8. Bioanalysis. 2018. PMID: 29516741

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