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The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress.
Sagliocchi S, Cicatiello AG, Di Cicco E, Ambrosio R, Miro C, Di Girolamo D, Nappi A, Mancino G, De Stefano MA, Luongo C, Raia M, Ogawa-Wong AN, Zavacki AM, Paladino S, Salvatore D, Dentice M. Sagliocchi S, et al. Among authors: nappi a. Redox Biol. 2019 Jun;24:101228. doi: 10.1016/j.redox.2019.101228. Epub 2019 May 22. Redox Biol. 2019. PMID: 31153038 Free PMC article.
Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch.
Miro C, Di Cicco E, Ambrosio R, Mancino G, Di Girolamo D, Cicatiello AG, Sagliocchi S, Nappi A, De Stefano MA, Luongo C, Antonini D, Visconte F, Varricchio S, Ilardi G, Del Vecchio L, Staibano S, Boelen A, Blanpain C, Missero C, Salvatore D, Dentice M. Miro C, et al. Among authors: nappi a. Nat Commun. 2019 Nov 27;10(1):5410. doi: 10.1038/s41467-019-13140-2. Nat Commun. 2019. PMID: 31776338 Free PMC article.
Author Correction: Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch.
Miro C, Di Cicco E, Ambrosio R, Mancino G, Di Girolamo D, Cicatiello AG, Sagliocchi S, Nappi A, De Stefano MA, Luongo C, Antonini D, Visconte F, Varricchio S, Ilardi G, Del Vecchio L, Staibano S, Boelen A, Blanpain C, Missero C, Salvatore D, Dentice M. Miro C, et al. Among authors: nappi a. Nat Commun. 2020 Jan 8;11(1):245. doi: 10.1038/s41467-019-13904-w. Nat Commun. 2020. PMID: 31913269 Free PMC article.
The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation.
Mancino G, Sibilio A, Luongo C, Di Cicco E, Miro C, Cicatiello AG, Nappi A, Sagliocchi S, Ambrosio R, De Stefano MA, Di Girolamo D, Porcelli T, Murolo M, Saracino F, Perruolo G, Formisano P, Stornaiuolo M, Dentice M. Mancino G, et al. Among authors: nappi a. Thyroid. 2020 Jul;30(7):1066-1078. doi: 10.1089/thy.2019.0557. Epub 2020 Apr 29. Thyroid. 2020. PMID: 32111151
The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas.
Nappi A, Di Cicco E, Miro C, Cicatiello AG, Sagliocchi S, Mancino G, Ambrosio R, Luongo C, Di Girolamo D, De Stefano MA, Porcelli T, Stornaiuolo M, Dentice M. Nappi A, et al. Cancers (Basel). 2020 Mar 18;12(3):715. doi: 10.3390/cancers12030715. Cancers (Basel). 2020. PMID: 32197405 Free PMC article.
Deiodinases and Cancer.
Nappi A, De Stefano MA, Dentice M, Salvatore D. Nappi A, et al. Endocrinology. 2021 Apr 1;162(4):bqab016. doi: 10.1210/endocr/bqab016. Endocrinology. 2021. PMID: 33539515 Free PMC article. Review.
Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas.
Miro C, Nappi A, Cicatiello AG, Di Cicco E, Sagliocchi S, Murolo M, Belli V, Troiani T, Albanese S, Amiranda S, Zavacki AM, Stornaiuolo M, Mancini M, Salvatore D, Dentice M. Miro C, et al. Among authors: nappi a. Cancers (Basel). 2021 Jun 1;13(11):2743. doi: 10.3390/cancers13112743. Cancers (Basel). 2021. PMID: 34205977 Free PMC article.
294 results