Füsser FT - Search Results

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Novel starting points for fragment-based drug design against mycobacterial thioredoxin reductase identified using crystallographic fragment screening.

Füsser FT, Wollenhaupt J, Weiss MS, Kümmel D, Koch O. Füsser FT, et al. Acta Crystallogr D Struct Biol. 2023 Sep 1;79(Pt 9):857-865. doi: 10.1107/S2059798323005223. Epub 2023 Aug 14. Acta Crystallogr D Struct Biol. 2023. PMID: 37574972 Free PMC article.

Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.

Marchetti GM, Füsser F, Singh RK, Brummel M, Koch O, Kümmel D, Hippler M. Marchetti GM, et al. J Struct Biol. 2022 Mar;214(1):107829. doi: 10.1016/j.jsb.2021.107829. Epub 2021 Dec 30. J Struct Biol. 2022. PMID: 34974142

Unveiling the Structure-Activity Relationships at the Orthosteric Binding Site of P2X Ion Channels: The Route to Selectivity.

Isaak A, Dobelmann C, Füsser FT, Erlitz KS, Koch O, Junker A. Isaak A, et al. Among authors: fusser ft. J Med Chem. 2022 Aug 25;65(16):11291-11308. doi: 10.1021/acs.jmedchem.2c00812. Epub 2022 Aug 5. J Med Chem. 2022. PMID: 35930402

Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists.

Patberg M, Isaak A, Füsser F, Ortiz Zacarías NV, Vinnenberg L, Schulte J, Michetti L, Grey L, van der Horst C, Hundehege P, Koch O, Heitman LH, Budde T, Junker A. Patberg M, et al. Eur J Med Chem. 2021 Dec 15;226:113838. doi: 10.1016/j.ejmech.2021.113838. Epub 2021 Sep 16. Eur J Med Chem. 2021. PMID: 34571173

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