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MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT, Smith AL, Godfrey L, Dopico-Fernandez AM, Denny N, Harman JR, Hamley JC, Jackson NE, Chahrour C, Riva S, Rice S, Kim J, Basrur V, Fermin D, Elenitoba-Johnson K, Roeder RG, Allis CD, Roberts I, Roy A, Geng H, Davies JOJ, Milne TA. Crump NT, et al. Among authors: chahrour c. Nat Commun. 2023 Aug 25;14(1):5208. doi: 10.1038/s41467-023-40981-9. Nat Commun. 2023. PMID: 37626123 Free PMC article.
Endothelial sensing of AHR ligands regulates intestinal homeostasis.
Wiggins BG, Wang YF, Burke A, Grunberg N, Vlachaki Walker JM, Dore M, Chahrour C, Pennycook BR, Sanchez-Garrido J, Vernia S, Barr AR, Frankel G, Birdsey GM, Randi AM, Schiering C. Wiggins BG, et al. Among authors: chahrour c. Nature. 2023 Sep;621(7980):821-829. doi: 10.1038/s41586-023-06508-4. Epub 2023 Aug 16. Nature. 2023. PMID: 37586410 Free PMC article.
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
de Jesus DS, Mak TCS, Wang YF, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM, Distaso W, Salem V, Tomas A, Stoffel M, Rutter GA, Latreille M. de Jesus DS, et al. Among authors: chahrour cm. Mol Metab. 2021 Nov;53:101248. doi: 10.1016/j.molmet.2021.101248. Epub 2021 May 12. Mol Metab. 2021. PMID: 33989778 Free PMC article.