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Page 1
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert T, Hsu CJ, Becker AL, Graessle S, Horne A, Bemmann F, Zhang Q, Heuser M, Vasioukhin V, Scholl S, Hochhaus A, Siegerist F, Endlich N, Bullinger L, Lane SW, Haas S, Schnoeder TM, Heidel FH. Eifert T, et al. Among authors: lane sw. Leukemia. 2023 Oct;37(10):2027-2035. doi: 10.1038/s41375-023-02005-9. Epub 2023 Aug 16. Leukemia. 2023. PMID: 37587260 Free PMC article.
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Lane SW, et al. Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15. Blood. 2011. PMID: 21765021 Free PMC article.
The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.
Heidel FH, Bullinger L, Arreba-Tutusaus P, Wang Z, Gaebel J, Hirt C, Niederwieser D, Lane SW, Döhner K, Vasioukhin V, Fischer T, Armstrong SA. Heidel FH, et al. Among authors: lane sw. J Exp Med. 2013 Jan 14;210(1):15-22. doi: 10.1084/jem.20120596. Epub 2012 Dec 31. J Exp Med. 2013. PMID: 23277453 Free PMC article.
Epo-induced erythroid maturation is dependent on Plcγ1 signaling.
Schnöder TM, Arreba-Tutusaus P, Griehl I, Bullinger L, Buschbeck M, Lane SW, Döhner K, Plass C, Lipka DB, Heidel FH, Fischer T. Schnöder TM, et al. Among authors: lane sw. Cell Death Differ. 2015 Jun;22(6):974-85. doi: 10.1038/cdd.2014.186. Epub 2014 Nov 14. Cell Death Differ. 2015. PMID: 25394487 Free PMC article.
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
Bruedigam C, Bagger FO, Heidel FH, Paine Kuhn C, Guignes S, Song A, Austin R, Vu T, Lee E, Riyat S, Moore AS, Lock RB, Bullinger L, Hill GR, Armstrong SA, Williams DA, Lane SW. Bruedigam C, et al. Among authors: lane sw. Cell Stem Cell. 2014 Dec 4;15(6):775-90. doi: 10.1016/j.stem.2014.11.010. Cell Stem Cell. 2014. PMID: 25479751 Free PMC article.
Hacking the stem cell niche.
Lane SW, Heidel FH. Lane SW, et al. Blood. 2017 Jun 1;129(22):2951-2952. doi: 10.1182/blood-2017-04-777789. Blood. 2017. PMID: 28572172 Free article. No abstract available.
Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes.
Chong CE, Venugopal P, Stokes PH, Lee YK, Brautigan PJ, Yeung DTO, Babic M, Engler GA, Lane SW, Klingler-Hoffmann M, Matthews JM, D'Andrea RJ, Brown AL, Hahn CN, Scott HS. Chong CE, et al. Among authors: lane sw. Leukemia. 2018 Jan;32(1):194-202. doi: 10.1038/leu.2017.196. Epub 2017 Jun 23. Leukemia. 2018. PMID: 28642594 Free PMC article.
Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin S, Straube J, Cooper L, Vu T, Song A, Bywater M, Baxter E, Heidecker M, Wackrow B, Porter A, Ling V, Green J, Austin R, Kazakoff S, Waddell N, Hesson LB, Pimanda JE, Stegelmann F, Bullinger L, Döhner K, Rampal RK, Heckl D, Hill GR, Lane SW. Jacquelin S, et al. Among authors: lane sw. Blood. 2018 Dec 27;132(26):2707-2721. doi: 10.1182/blood-2018-04-846220. Epub 2018 Oct 26. Blood. 2018. PMID: 30366920 Free article.
Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Austin RJ, Straube J, Bruedigam C, Pali G, Jacquelin S, Vu T, Green J, Gräsel J, Lansink L, Cooper L, Lee SJ, Chen NT, Lee CW, Haque A, Heidel FH, D'Andrea R, Hill GR, Mullally A, Milsom MD, Bywater M, Lane SW. Austin RJ, et al. Among authors: lane sw. Leukemia. 2020 Apr;34(4):1075-1089. doi: 10.1038/s41375-019-0638-y. Epub 2019 Nov 15. Leukemia. 2020. PMID: 31732720 Free PMC article.
115 results