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Correction to: The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability.
Russell H, Kedzierska K, Buchanan DD, Thomas R, Tham E, Mints M, Keränen A, Giles GG, Southey MC, Milne RL, Tomlinson I, Church D, Spurdle AB, O'Mara TA, Lewis A. Russell H, et al. Among authors: lewis a. Clin Epigenetics. 2021 Apr 1;13(1):69. doi: 10.1186/s13148-021-01058-w. Clin Epigenetics. 2021. PMID: 33794988 Free PMC article. No abstract available.
Five endometrial cancer risk loci identified through genome-wide association analysis.
Cheng TH, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, Lewis A, French JD, Freeman-Mills L, Church D, Gorman M, Martin L; National Study of Endometrial Cancer Genetics Group (NSECG); Hodgson S, Webb PM; Australian National Endometrial Cancer Study Group (ANECS); Attia J, Holliday EG, McEvoy M, Scott RJ, Henders AK, Martin NG, Montgomery GW, Nyholt DR, Ahmed S, Healey CS, Shah M, Dennis J, Fasching PA, Beckmann MW, Hein A, Ekici AB, Hall P, Czene K, Darabi H, Li J, Dörk T, Dürst M, Hillemanns P, Runnebaum I, Amant F, Schrauwen S, Zhao H, Lambrechts D, Depreeuw J, Dowdy SC, Goode EL, Fridley BL, Winham SJ, Njølstad TS, Salvesen HB, Trovik J, Werner HM, Ashton K, Otton G, Proietto T, Liu T, Mints M, Tham E; RENDOCAS; Consortium C, Jun Li M, Yip SH, Wang J, Bolla MK, Michailidou K, Wang Q, Tyrer JP, Dunlop M, Houlston R, Palles C, Hopper JL; AOCS Group; Peto J, Swerdlow AJ, Burwinkel B, Brenner H, Meindl A, Brauch H, Lindblom A, Chang-Claude J, Couch FJ, Giles GG, Kristensen VN, Cox A, Cunningham JM, Pharoah PDP, Dunning AM, Edwards SL, Easton DF, Tomlinson I, Spurdle AB. Cheng TH, et al. Among authors: lewis a. Nat Genet. 2016 Jun;48(6):667-674. doi: 10.1038/ng.3562. Epub 2016 May 2. Nat Genet. 2016. PMID: 27135401 Free PMC article.
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression.
Thomas R, Trapani D, Goodyer-Sait L, Tomkova M, Fernandez-Rozadilla C, Sahnane N, Woolley C, Davis H, Chegwidden L, Kriaucionis S, Maughan T, Leedham S, Palles C, Furlan D, Tomlinson I, Lewis A. Thomas R, et al. Among authors: lewis a. Sci Rep. 2019 Sep 17;9(1):13463. doi: 10.1038/s41598-019-49952-x. Sci Rep. 2019. PMID: 31530880 Free PMC article.
4,493 results