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Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
Schulze CJ, Seamon KJ, Zhao Y, Yang YC, Cregg J, Kim D, Tomlinson A, Choy TJ, Wang Z, Sang B, Pourfarjam Y, Lucas J, Cuevas-Navarro A, Ayala-Santos C, Vides A, Li C, Marquez A, Zhong M, Vemulapalli V, Weller C, Gould A, Whalen DM, Salvador A, Milin A, Saldajeno-Concar M, Dinglasan N, Chen A, Evans J, Knox JE, Koltun ES, Singh M, Nichols R, Wildes D, Gill AL, Smith JAM, Lito P. Schulze CJ, et al. Among authors: vemulapalli v. Science. 2023 Aug 18;381(6659):794-799. doi: 10.1126/science.adg9652. Epub 2023 Aug 17. Science. 2023. PMID: 37590355 Free PMC article.
Targeted Degradation of the Oncogenic Phosphatase SHP2.
Vemulapalli V, Donovan KA, Seegar TCM, Rogers JM, Bae M, Lumpkin RJ, Cao R, Henke MT, Ray SS, Fischer ES, Cuny GD, Blacklow SC. Vemulapalli V, et al. Biochemistry. 2021 Aug 31;60(34):2593-2609. doi: 10.1021/acs.biochem.1c00377. Epub 2021 Aug 19. Biochemistry. 2021. PMID: 34411482 Free PMC article.
Identification and validation of N-acetylputrescine in combination with non-canonical clinical features as a Parkinson's disease biomarker panel.
Peng KW, Klotz A, Guven A, Kapadnis U, Ravipaty S, Tolstikov V, Vemulapalli V, Rodrigues LO, Li H, Kellogg MD, Kausar F, Rees L, Sarangarajan R, Schüle B, Langston W, Narain P, Narain NR, Kiebish MA. Peng KW, et al. Among authors: vemulapalli v. Sci Rep. 2024 May 2;14(1):10036. doi: 10.1038/s41598-024-60872-3. Sci Rep. 2024. PMID: 38693432 Free PMC article.
34 results