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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.
DiGruccio MR, Mawla AM, Donaldson CJ, Noguchi GM, Vaughan J, Cowing-Zitron C, van der Meulen T, Huising MO. DiGruccio MR, et al. Among authors: mawla am. Mol Metab. 2016 May 3;5(7):449-458. doi: 10.1016/j.molmet.2016.04.007. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408771 Free PMC article.
Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
van der Meulen T, Mawla AM, DiGruccio MR, Adams MW, Nies V, Dólleman S, Liu S, Ackermann AM, Cáceres E, Hunter AE, Kaestner KH, Donaldson CJ, Huising MO. van der Meulen T, et al. Among authors: mawla am. Cell Metab. 2017 Apr 4;25(4):911-926.e6. doi: 10.1016/j.cmet.2017.03.017. Cell Metab. 2017. PMID: 28380380 Free PMC article.
Artemether Does Not Turn α Cells into β Cells.
van der Meulen T, Lee S, Noordeloos E, Donaldson CJ, Adams MW, Noguchi GM, Mawla AM, Huising MO. van der Meulen T, et al. Among authors: mawla am. Cell Metab. 2018 Jan 9;27(1):218-225.e4. doi: 10.1016/j.cmet.2017.10.002. Epub 2017 Nov 2. Cell Metab. 2018. PMID: 29103923 Free PMC article.
IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes.
Blencowe M, Furterer A, Wang Q, Gao F, Rosenberger M, Pei L, Nomoto H, Mawla AM, Huising MO, Coppola G, Yang X, Butler PC, Gurlo T. Blencowe M, et al. Among authors: mawla am. Diabetologia. 2022 Jan;65(1):173-187. doi: 10.1007/s00125-021-05569-2. Epub 2021 Sep 23. Diabetologia. 2022. PMID: 34554282 Free PMC article.
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.
Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M, Montoya-Oviedo N, Homan EA, Imai N, Gilani A, Liu C, Naji A, Yang B, Chong ACN, Cohen DE, Chen S, Cao J, Pitt GS, Huising MO, Betel D, Lo JC. Rubio-Navarro A, et al. Among authors: mawla am. Nat Cell Biol. 2023 Apr;25(4):565-578. doi: 10.1038/s41556-023-01103-1. Epub 2023 Mar 16. Nat Cell Biol. 2023. PMID: 36928765 Free PMC article.
25 results